Pseudomonas aeruginosa UCBPP-PA14, PA14_65605 (parC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0009340 DNA topoisomerase IV complex
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA4964
 ECO:0000249
sequence similarity evidence used in automatic assertion		 10049263
Biological Process GO:0006265 DNA topological change
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA4964
 ECO:0000249
sequence similarity evidence used in automatic assertion		 10049263
Molecular Function GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA4964
 ECO:0000249
sequence similarity evidence used in automatic assertion		 10049263
Cellular Component GO:0005694 chromosome
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00936
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006265 DNA topological change
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03989
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00521
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006259 DNA metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.199.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03989
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003916 DNA topoisomerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03989
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03989
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other UCBPP-PA14 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00187 TOP4c IPR002205 DNA topoisomerase, type IIA, domain A 34 474 0.0
SMART SM00434 topIV4 IPR002205 DNA topoisomerase, type IIA, domain A 15 465 0.0
FunFam G3DSA:3.30.1360.40:FF:000005 DNA topoisomerase 4 subunit A - - 242 335 4.5E-53
SUPERFAMILY SSF101904 GyrA/ParC C-terminal domain-like IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal 501 750 5.49E-53
FunFam G3DSA:2.120.10.90:FF:000003 DNA topoisomerase 4 subunit A - - 498 748 1.4E-128
Gene3D G3DSA:2.120.10.90 - IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal 498 749 1.0E-46
Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. IPR005742 DNA topoisomerase IV, subunit A, Gram-negative 8 747 34.130394
Gene3D G3DSA:3.90.199.10 Topoisomerase II, domain 5 IPR013758 DNA topoisomerase, type IIA, domain A, alpha-beta 36 487 0.0
FunFam G3DSA:1.10.268.10:FF:000001 DNA gyrase subunit A - - 364 459 1.1E-30
Gene3D G3DSA:1.10.268.10 Topoisomerase, domain 3 IPR013757 DNA topoisomerase, type IIA, alpha-helical domain superfamily 373 458 0.0
NCBIfam TIGR01062 JCVI: DNA topoisomerase IV subunit A - - 12 745 0.0
Gene3D G3DSA:3.30.1360.40 - - - 242 335 0.0
Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A IPR002205 DNA topoisomerase, type IIA, domain A 36 472 0.0
Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat 649 689 3.6E-5
PANTHER PTHR43493 DNA GYRASE/TOPOISOMERASE SUBUNIT A - - 8 715 0.0
Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat 602 643 0.0049
SUPERFAMILY SSF56719 Type II DNA topoisomerase IPR013760 DNA topoisomerase, type IIA-like domain superfamily 35 487 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.