Pseudomonas aeruginosa UCBPP-PA14, PA14_46470 (pdxB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0033711 4-phosphoerythronate dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01825
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00389
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00389
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0046983 protein dimerization activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF11890
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008615 pyridoxine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01825
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01825
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class
Carbon compound catabolism Other UCBPP-PA14 genes in this class
Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00750 Vitamin B6 metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF52283 Formate/glycerate dehydrogenase catalytic domain-like - - 5 103 1.36E-15
Hamap MF_01825 Erythronate-4-phosphate dehydrogenase [pdxB]. IPR020921 Erythronate-4-phosphate dehydrogenase 1 363 44.922489
CDD cd12158 ErythrP_dh IPR020921 Erythronate-4-phosphate dehydrogenase 2 350 0.0
Gene3D G3DSA:3.40.50.720 - - - 92 257 2.2E-118
Pfam PF11890 Domain of unknown function (DUF3410) IPR024531 Erythronate-4-phosphate dehydrogenase, dimerisation domain 289 376 7.5E-22
FunFam G3DSA:3.40.50.720:FF:000093 Erythronate-4-phosphate dehydrogenase - - 92 257 3.3E-75
Gene3D G3DSA:3.40.50.720 - - - 1 277 2.2E-118
Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain 107 256 6.0E-35
PANTHER PTHR42938 FORMATE DEHYDROGENASE 1 - - 33 274 2.0E-37
Gene3D G3DSA:3.30.1370.170 - IPR038251 PdxB, dimerisation domain superfamily 293 380 9.3E-28
Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 33 277 4.6E-15
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 91 258 3.66E-37

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.