Pseudomonas aeruginosa UCBPP-PA14, PA14_40290 (lasA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004175 endopeptidase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA1871
 ECO:0000249
sequence similarity evidence used in automatic assertion		 9642203
Molecular Function GO:0004222 metalloendopeptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00933
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006508 proteolysis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00933
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Translation, post-translational modification, degradation Other UCBPP-PA14 genes in this class
Secreted Factors (toxins, enzymes, alginate) Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau02024 Quorum sensing 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51261 Duplicated hybrid motif IPR011055 Duplicated hybrid motif 226 365 5.18E-18
PRINTS PR00933 B-lytic metalloendopeptidase (M23) signature IPR000841 Peptidase M23A, B-lytic metalloendopeptidase 244 265 1.6E-57
FunFam G3DSA:2.70.70.10:FF:000044 Protease LasA - - 237 418 4.0E-129
PRINTS PR00933 B-lytic metalloendopeptidase (M23) signature IPR000841 Peptidase M23A, B-lytic metalloendopeptidase 293 311 1.6E-57
Pfam PF01551 Peptidase family M23 IPR016047 Peptidase M23 286 367 1.6E-11
Gene3D G3DSA:2.70.70.10 Glucose Permease (Domain IIA) IPR011055 Duplicated hybrid motif 237 418 1.7E-53
CDD cd12797 M23_peptidase - - 287 361 2.6346E-16
PANTHER PTHR21666 PEPTIDASE-RELATED - - 201 368 3.5E-10
PRINTS PR00933 B-lytic metalloendopeptidase (M23) signature IPR000841 Peptidase M23A, B-lytic metalloendopeptidase 345 365 1.6E-57
PRINTS PR00933 B-lytic metalloendopeptidase (M23) signature IPR000841 Peptidase M23A, B-lytic metalloendopeptidase 266 284 1.6E-57
PRINTS PR00933 B-lytic metalloendopeptidase (M23) signature IPR000841 Peptidase M23A, B-lytic metalloendopeptidase 372 395 1.6E-57

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.