Pseudomonas aeruginosa UCBPP-PA14, PA14_38440 (gnyD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008470 isovaleryl-CoA dehydrogenase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA2015
 ECO:0000249
sequence similarity evidence used in automatic assertion		 16517656
Biological Process GO:0008300 isoprenoid catabolic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA2015
 ECO:0000249
sequence similarity evidence used in automatic assertion		 16517656
Molecular Function GO:0050660 flavin adenine dinucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02771
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00441
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003995 acyl-CoA dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01156
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other UCBPP-PA14 genes in this class
Fatty acid and phospholipid metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Acyclic isoprenoid catabolism ECO:0000037
not_recorded
KEGG pau00280 Valine, leucine and isoleucine degradation 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal 14 123 4.6E-38
SUPERFAMILY SSF47203 Acyl-CoA dehydrogenase C-terminal domain-like IPR036250 Acyl-CoA dehydrogenase-like, C-terminal 233 385 6.28E-46
FunFam G3DSA:2.40.110.10:FF:000004 Isovaleryl-CoA dehydrogenase, mitochondrial - - 126 239 4.0E-57
Pfam PF02770 Acyl-CoA dehydrogenase, middle domain IPR006091 Acyl-CoA oxidase/dehydrogenase, middle domain 127 222 7.8E-27
Gene3D G3DSA:2.40.110.10 - IPR046373 Acyl-CoA oxidase/dehydrogenase, middle domain superfamily 126 239 5.0E-43
PIRSF PIRSF016578 PIGM - - 13 387 3.2E-14
Gene3D G3DSA:1.10.540.10 - IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily 2 124 1.1E-39
Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain IPR009075 Acyl-CoA dehydrogenase/oxidase, C-terminal 234 382 4.1E-41
PANTHER PTHR43884 ACYL-COA DEHYDROGENASE - - 12 385 0.0
Gene3D G3DSA:1.20.140.10 - - - 240 382 1.1E-46
CDD cd01156 IVD IPR034183 Isovaleryl-CoA dehydrogenase 9 384 0.0
FunFam G3DSA:1.20.140.10:FF:000003 isovaleryl-CoA dehydrogenase, mitochondrial - - 240 384 3.7E-80
FunFam G3DSA:1.10.540.10:FF:000022 Isovaleryl-CoA dehydrogenase isoform 2 - - 2 124 7.4E-58
SUPERFAMILY SSF56645 Acyl-CoA dehydrogenase NM domain-like IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily 5 247 1.83E-86

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.