Pseudomonas aeruginosa UCBPP-PA14, PA14_38410 (amrB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0015562 efflux transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00915
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055085 transmembrane transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00702
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00702
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0022857 transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00702
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0042908 xenobiotic transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00915
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Antibiotic resistance and susceptibility Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01501 beta-Lactam resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.70.1440 Multidrug efflux transporter AcrB pore domain - - 669 867 0.0
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 469 492 1.2E-105
SUPERFAMILY SSF82714 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains 181 270 4.58E-18
PANTHER PTHR32063 - IPR001036 Acriflavin resistance protein 2 1029 0.0
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 36 54 1.2E-105
Gene3D G3DSA:3.30.70.1430 Multidrug efflux transporter AcrB pore domain - - 38 817 0.0
Gene3D G3DSA:3.30.2090.10 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains 179 277 0.0
SUPERFAMILY SSF82714 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains 719 805 5.62E-20
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 362 383 1.2E-105
SUPERFAMILY SSF82693 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains - - 135 329 6.98E-26
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 444 467 1.2E-105
SUPERFAMILY SSF82693 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains - - 38 130 3.14E-24
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 390 414 1.2E-105
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 618 632 1.2E-105
Pfam PF00873 AcrB/AcrD/AcrF family IPR001036 Acriflavin resistance protein 1 1022 0.0
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 8 32 1.2E-105
SUPERFAMILY SSF82693 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains - - 564 667 1.2E-24
FunFam G3DSA:1.20.1640.10:FF:000001 Efflux pump membrane transporter - - 322 509 2.9E-71
NCBIfam TIGR00915 JCVI: efflux RND transporter permease subunit IPR004764 Multidrug resistance protein MdtF-like 1 1032 0.0
Gene3D G3DSA:1.20.1640.10 Multidrug efflux transporter AcrB transmembrane domain - - 7 514 0.0
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 551 568 1.2E-105
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 335 358 1.2E-105
FunFam G3DSA:3.30.70.1430:FF:000001 Efflux pump membrane transporter - - 38 137 1.1E-26
SUPERFAMILY SSF82866 Multidrug efflux transporter AcrB transmembrane domain - - 803 1025 1.57E-44
SUPERFAMILY SSF82866 Multidrug efflux transporter AcrB transmembrane domain - - 295 497 1.07E-48
Gene3D G3DSA:3.30.70.1430 Multidrug efflux transporter AcrB pore domain - - 569 668 0.0
Gene3D G3DSA:3.30.2090.10 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains 721 809 0.0
Gene3D G3DSA:3.30.70.1320 Multidrug efflux transporter AcrB pore domain like - - 132 330 0.0
Gene3D G3DSA:1.20.1640.10 Multidrug efflux transporter AcrB transmembrane domain - - 515 1019 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.