Pseudomonas aeruginosa UCBPP-PA14, PA14_30650 (gacA)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:1900190	regulation of single-species biofilm formation	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	11401724	Reviewed by curator
Biological Process	GO:1900233	positive regulation of single-species biofilm formation on inanimate substrate	ISS Inferred from Sequence or Structural Similarity Term mapped from: PseudoCAP:PA2586	ECO:0000249 sequence similarity evidence used in automatic assertion	11401724
Biological Process	GO:0009405	pathogenesis	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	12578988	Reviewed by curator
Biological Process	GO:0006355	regulation of transcription, DNA-templated	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF46894	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0000160	phosphorelay signal transduction system	ISM Inferred from Sequence Model Term mapped from: InterPro:SM00448	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003677	DNA binding	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF46894	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other UCBPP-PA14 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pau02025	Biofilm formation - Pseudomonas aeruginosa	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pau02020	Two-component system	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PRINTS	PR00038	LuxR bacterial regulatory protein HTH signature	IPR000792	Transcription regulator LuxR, C-terminal	150	164	5.5E-5
CDD	cd17535	REC_NarL-like	-	-	4	120	1.50022E-49
SMART	SM00448	REC_2	IPR001789	Signal transduction response regulator, receiver domain	2	115	6.8E-30
SMART	SM00421	luxrmega5	IPR000792	Transcription regulator LuxR, C-terminal	147	204	4.4E-18
Gene3D	G3DSA:3.40.50.2300	-	-	-	2	210	8.2E-61
SUPERFAMILY	SSF46894	C-terminal effector domain of the bipartite response regulators	IPR016032	Signal transduction response regulator, C-terminal effector	132	211	2.07E-18
PRINTS	PR00038	LuxR bacterial regulatory protein HTH signature	IPR000792	Transcription regulator LuxR, C-terminal	180	192	5.5E-5
CDD	cd06170	LuxR_C_like	IPR000792	Transcription regulator LuxR, C-terminal	150	206	4.63353E-13
SUPERFAMILY	SSF52172	CheY-like	IPR011006	CheY-like superfamily	1	132	3.27E-34
Pfam	PF00196	Bacterial regulatory proteins, luxR family	IPR000792	Transcription regulator LuxR, C-terminal	148	204	1.1E-14
PANTHER	PTHR43214	TWO-COMPONENT RESPONSE REGULATOR	IPR039420	Transcriptional regulatory protein WalR-like	2	208	3.1E-50
PRINTS	PR00038	LuxR bacterial regulatory protein HTH signature	IPR000792	Transcription regulator LuxR, C-terminal	164	180	5.5E-5
FunFam	G3DSA:3.40.50.2300:FF:000015	Two-component response regulator UvrY	-	-	2	210	3.5E-121
Pfam	PF00072	Response regulator receiver domain	IPR001789	Signal transduction response regulator, receiver domain	4	116	2.5E-28

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.