Pseudomonas aeruginosa UCBPP-PA14, PA14_25920 (cobM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009236 cobalamin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd11641
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0046026 precorrin-4 C11-methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd11641
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008168 methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00590
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00860 Porphyrin and chlorophyll metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR45790 SIROHEME SYNTHASE-RELATED - - 2 232 8.0E-61
SUPERFAMILY SSF53790 Tetrapyrrole methylase IPR035996 Tetrapyrrole methylase superfamily 2 229 1.27E-68
NCBIfam TIGR01465 JCVI: precorrin-4 C(11)-methyltransferase IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase 3 247 1.5E-97
CDD cd11641 Precorrin-4_C11-MT IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase 6 228 2.89573E-126
Gene3D G3DSA:3.40.1010.10 - IPR014777 Tetrapyrrole methylase, subdomain 1 1 109 2.3E-31
Gene3D G3DSA:3.30.950.10 - IPR014776 Tetrapyrrole methylase, subdomain 2 111 231 1.7E-35
Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases IPR000878 Tetrapyrrole methylase 2 206 5.4E-48
Coils Coil Coil - - 51 71 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.