Pseudomonas aeruginosa UCBPP-PA14, PA14_23260 (gyrA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005694 chromosome
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01897
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00187
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00187
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00187
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006265 DNA topological change
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00187
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003916 DNA topoisomerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03989
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006259 DNA metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.199.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other UCBPP-PA14 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A IPR002205 DNA topoisomerase, type IIA, domain A 32 507 0.0
Gene3D G3DSA:1.10.268.10 Topoisomerase, domain 3 IPR013757 DNA topoisomerase, type IIA, alpha-helical domain superfamily 371 493 0.0
Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat 788 833 2.2E-12
NCBIfam TIGR01063 JCVI: DNA gyrase subunit A - - 8 638 0.0
Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat 689 732 2.8E-8
SUPERFAMILY SSF56719 Type II DNA topoisomerase IPR013760 DNA topoisomerase, type IIA-like domain superfamily 30 523 0.0
SMART SM00434 topIV4 IPR002205 DNA topoisomerase, type IIA, domain A 11 500 0.0
Gene3D G3DSA:3.30.1360.40 - - - 236 334 0.0
CDD cd00187 TOP4c IPR002205 DNA topoisomerase, type IIA, domain A 30 510 0.0
Coils Coil Coil - - 500 520 -
MobiDBLite mobidb-lite consensus disorder prediction - - 881 921 -
PANTHER PTHR43493 DNA GYRASE/TOPOISOMERASE SUBUNIT A - - 4 887 0.0
FunFam G3DSA:3.30.1360.40:FF:000002 DNA gyrase subunit A - - 236 334 2.0E-41
Gene3D G3DSA:2.120.10.90 - IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal 532 885 9.2E-127
Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat 591 638 1.6E-8
Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat 539 586 1.5E-8
Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat 737 781 1.9E-13
Gene3D G3DSA:3.90.199.10 Topoisomerase II, domain 5 IPR013758 DNA topoisomerase, type IIA, domain A, alpha-beta 32 522 0.0
Hamap MF_01897 DNA gyrase subunit A [gyrA]. IPR005743 DNA gyrase, subunit A 1 885 23.955879
MobiDBLite mobidb-lite consensus disorder prediction - - 890 905 -
SUPERFAMILY SSF101904 GyrA/ParC C-terminal domain-like IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal 534 898 1.7E-99
Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat 837 883 2.4E-12
FunFam G3DSA:3.90.199.10:FF:000001 DNA gyrase subunit A - - 32 251 8.0E-113

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.