Pseudomonas aeruginosa UCBPP-PA14, PA14_12390 (hemL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0033014 tetrapyrrole biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00713
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0042286 glutamate-1-semialdehyde 2,1-aminomutase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00713
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008483 transaminase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00202
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030170 pyridoxal phosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00202
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc tetrapyrrole biosynthesis I (from glutamate) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
PseudoCAP biosynthesis of tetrapyrroles (porphyrine biosynthesis) ECO:0000037
not_recorded
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00860 Porphyrin and chlorophyll metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase, domain 1 IPR015422 Pyridoxal phosphate-dependent transferase, small domain 6 419 0.0
Gene3D G3DSA:3.40.640.10 - IPR015421 Pyridoxal phosphate-dependent transferase, major domain 69 317 0.0
PANTHER PTHR43713 GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE - - 2 424 0.0
Pfam PF00202 Aminotransferase class-III IPR005814 Aminotransferase class-III 32 394 3.4E-78
SUPERFAMILY SSF53383 PLP-dependent transferases IPR015424 Pyridoxal phosphate-dependent transferase 2 424 0.0
NCBIfam TIGR00713 JCVI: glutamate-1-semialdehyde 2,1-aminomutase IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase 4 424 0.0
CDD cd00610 OAT_like IPR005814 Aminotransferase class-III 7 423 0.0
FunFam G3DSA:3.40.640.10:FF:000021 Glutamate-1-semialdehyde 2,1-aminomutase - - 69 317 4.8E-127
Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase 3 426 105.590179

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.