Pseudomonas aeruginosa 3581, AJ68_02882

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa 3581
GCF_000629165.1|latest
Locus Tag
AJ68_02882
Name
Replicon adTwT-supercont1.7
Genomic location 330267 - 332243 (- strand)

Cross-References

RefSeq WP_003114166.1
GI 489205110
NCBI Locus Tag AJ68_02882

Product

Feature Type CDS
Coding Frame 1
Product Name
SDS hydrolase SdsA1
Synonyms
Evidence for Translation
Charge (pH 7) -8.84
Kyte-Doolittle Hydrophobicity Value -0.252
Molecular Weight (kDa) 72.6
Isoelectric Point (pI) 5.82

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5AJL HYDROLASE 02/25/15 Sdsa sulfatase tetragonal PSEUDOMONAS AERUGINOSA 3.45 X-RAY DIFFRACTION 100.0
2CG3 HYDROLASE 02/27/06 Crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa. PSEUDOMONAS AERUGINOSA 2.6 X-RAY DIFFRACTION 100.0
5A23 HYDROLASE 05/11/15 SdsA sulfatase triclinic form PSEUDOMONAS AERUGINOSA 2.41 X-RAY DIFFRACTION 100.0
2CFZ HYDROLASE 02/26/06 Crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, in complex with 1-dodecanol PSEUDOMONAS AERUGINOSA 2.05 X-RAY DIFFRACTION 100.0
2CG2 HYDROLASE 02/27/06 Crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, in complex with sulfate PSEUDOMONAS AERUGINOSA 2.1 X-RAY DIFFRACTION 100.0
5AIJ HYDROLASE 02/13/15 P. aeruginosa SdsA hexagonal polymorph PSEUDOMONAS AERUGINOSA 1.95 X-RAY DIFFRACTION 100.0
2CFU HYDROLASE 02/23/06 Crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, in complex with 1-decane-sulfonic-acid. PSEUDOMONAS AERUGINOSA 1.9 X-RAY DIFFRACTION 100.0

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
1-DODECANOL DB06894 DrugBank 5.1.4 Q9I5I9 SDS hydrolase SdsA1 100.0 658 0.0e+00
1-DECANE-SULFONIC-ACID DB06893 DrugBank 5.1.4 Q9I5I9 SDS hydrolase SdsA1 100.0 658 0.0e+00

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000715 (357 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: AJ68_02882

Human Homologs

References

No references are associated with this feature.