Pseudomonas putida HB3267, B479_13240 (ligD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01068
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003910 DNA ligase (ATP) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF04679
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF04679
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006310 DNA recombination
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF04679
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG ppuh03450 Non-homologous end-joining 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd07906 Adenylation_DNA_ligase_LigD_LigC - - 215 398 3.87829E-84
Pfam PF04679 ATP dependent DNA ligase C terminal region IPR012309 DNA ligase, ATP-dependent, C-terminal 416 512 1.2E-23
Gene3D G3DSA:3.30.1490.70 - - - 228 395 1.0E-44
NCBIfam TIGR02778 JCVI: non-homologous end-joining DNA ligase, polymerase domain IPR014145 DNA ligase D, polymerase domain 544 784 1.8E-84
Gene3D G3DSA:3.90.920.10 DNA primase, PRIM domain - - 550 830 3.3E-92
NCBIfam TIGR02779 JCVI: non-homologous end-joining DNA ligase, ligase domain IPR014146 DNA ligase D, ligase domain 217 518 2.6E-111
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 400 518 5.14E-29
SUPERFAMILY SSF56091 DNA ligase/mRNA capping enzyme, catalytic domain - - 203 398 2.88E-46
MobiDBLite mobidb-lite consensus disorder prediction - - 180 210 -
PANTHER PTHR42705 BIFUNCTIONAL NON-HOMOLOGOUS END JOINING PROTEIN LIGD - - 246 826 6.8E-102
MobiDBLite mobidb-lite consensus disorder prediction - - 1 26 -
NCBIfam TIGR02776 JCVI: DNA ligase D IPR014143 DNA ligase D 226 813 0.0
NCBIfam TIGR02777 JCVI: DNA ligase D, 3'-phosphoesterase domain IPR014144 DNA ligase D, 3'-phosphoesterase domain 5 160 4.4E-74
MobiDBLite mobidb-lite consensus disorder prediction - - 1 28 -
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 399 520 2.8E-37
Pfam PF01068 ATP dependent DNA ligase domain IPR012310 DNA ligase, ATP-dependent, central 215 397 5.6E-27
CDD cd04862 PaeLigD_Pol_like IPR033651 LigD polymerase domain, PaeLigD-type 560 784 1.44981E-111
Pfam PF13298 DNA polymerase Ligase (LigD) IPR014144 DNA ligase D, 3'-phosphoesterase domain 38 141 1.2E-39
CDD cd07971 OBF_DNA_ligase_LigD - - 400 517 2.11056E-53
Gene3D G3DSA:3.30.470.30 DNA ligase/mRNA capping enzyme - - 239 354 1.0E-44

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.