Pseudomonas aeruginosa 3575, AJ62_03305

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003911 DNA ligase (NAD+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF001604
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF001604
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF001604
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF52113 BRCT domain IPR036420 BRCT domain superfamily 714 788 5.23E-17
SMART SM00292 BRCT_7 IPR001357 BRCT domain 713 790 6.3E-9
Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type 419 458 1.4E-13
Gene3D G3DSA:1.10.150.20 - - - 529 611 1.9E-24
PANTHER PTHR23389 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 - - 16 770 5.6E-55
FunFam G3DSA:1.10.287.610:FF:000002 DNA ligase - - 2 67 2.6E-29
FunFam G3DSA:1.10.150.20:FF:000006 DNA ligase - - 530 609 3.4E-25
Gene3D G3DSA:3.40.50.10190 BRCT domain IPR036420 BRCT domain superfamily 702 788 2.0E-23
Gene3D G3DSA:1.10.287.610 Helix hairpin bin - - 1 67 8.2E-29
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 330 412 5.82E-28
CDD cd00114 LIGANc IPR013839 NAD-dependent DNA ligase, adenylation 9 329 0.0
FunFam G3DSA:3.30.470.30:FF:000001 DNA ligase - - 68 327 4.0E-107
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 329 402 8.1E-33
Gene3D G3DSA:6.20.10.30 - - - 403 453 2.4E-13
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 534 597 7.3E-21
Gene3D G3DSA:3.30.470.30 DNA ligase/mRNA capping enzyme - - 68 327 2.9E-98
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 618 704 7.41E-14
SMART SM00532 ligaN3 IPR013840 NAD-dependent DNA ligase, N-terminal 6 472 0.0
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 620 792 2.3E-31
NCBIfam TIGR00575 JCVI: DNA ligase (NAD(+)) LigA IPR001679 NAD-dependent DNA ligase 14 617 0.0
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 632 687 2.4E-8
SUPERFAMILY SSF56091 DNA ligase/mRNA capping enzyme, catalytic domain - - 3 328 2.16E-118
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 1 622 0.0
FunFam G3DSA:2.40.50.140:FF:000012 DNA ligase - - 329 402 5.5E-34
Pfam PF01653 NAD-dependent DNA ligase adenylation domain IPR013839 NAD-dependent DNA ligase, adenylation 7 330 7.2E-124
Hamap MF_01588 DNA ligase [ligA]. IPR001679 NAD-dependent DNA ligase 5 787 52.841911
Gene3D G3DSA:1.10.150.20 - - - 624 701 1.3E-11
Gene3D G3DSA:1.10.150.20 - - - 454 528 5.1E-28
FunFam G3DSA:1.10.150.20:FF:000007 DNA ligase - - 454 529 3.8E-30
CDD cd17748 BRCT_DNA_ligase_like - - 716 786 2.40783E-24
Pfam PF03120 NAD-dependent DNA ligase OB-fold domain IPR004150 NAD-dependent DNA ligase, OB-fold 334 410 3.5E-34
Pfam PF00533 BRCA1 C Terminus (BRCT) domain IPR001357 BRCT domain 713 787 2.2E-11
FunFam G3DSA:3.40.50.10190:FF:000069 DNA ligase - - 706 789 8.8E-42
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 416 603 1.37E-52

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.