Pseudomonas aeruginosa 3573, AJ60_00918

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0047919 GDP-mannose 6-dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF500135
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0042121 alginic acid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF500135
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00984
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR03026
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 1 195 2.91E-51
PIRSF PIRSF500135 GDPman_DH IPR028358 GDP-mannose 6-dehydrogenase 1 436 0.0
Gene3D G3DSA:3.40.50.720 - - - 235 436 3.3E-58
Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal 1 190 6.0E-63
Gene3D G3DSA:1.20.5.170 - - - 203 234 6.4E-20
PIRSF PIRSF000124 UDPglc_GDPman_dh IPR017476 UDP-glucose/GDP-mannose dehydrogenase 1 436 0.0
NCBIfam TIGR03026 JCVI: nucleotide sugar dehydrogenase IPR017476 UDP-glucose/GDP-mannose dehydrogenase 1 410 1.1E-130
SUPERFAMILY SSF48179 6-phosphogluconate dehydrogenase C-terminal domain-like IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily 204 300 7.48E-28
FunFam G3DSA:3.40.50.720:FF:000664 GDP-mannose 6-dehydrogenase - - 235 436 0.0
SUPERFAMILY SSF52413 UDP-glucose/GDP-mannose dehydrogenase C-terminal domain IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily 305 434 2.62E-25
SMART SM00984 UDPG_MGDP_dh_C_a_2_a IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal 317 425 2.2E-19
Gene3D G3DSA:3.40.50.720 - - - 1 202 5.9E-80
FunFam G3DSA:3.40.50.720:FF:000573 GDP-mannose 6-dehydrogenase - - 1 202 0.0
Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation 205 298 2.1E-28
Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal 318 405 2.6E-12
PANTHER PTHR43750 UDP-GLUCOSE 6-DEHYDROGENASE TUAD - - 1 404 3.1E-114

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.