Pseudomonas aeruginosa LES431, T223_30140

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0031419 cobalamin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02888
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02888
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02888
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pael00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pael01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pael00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 316 327 2.2E-18
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 508 535 2.2E-18
SUPERFAMILY SSF51998 PFL-like glycyl radical enzymes - - 15 690 0.0
CDD cd02888 RNR_II_dimer IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent 75 651 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 392 414 2.2E-18
FunFam G3DSA:3.20.70.20:FF:000040 Vitamin B12-dependent ribonucleotide reductase - - 1 652 0.0
NCBIfam TIGR02504 JCVI: adenosylcobalamin-dependent ribonucleoside-diphosphate reductase IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent 23 658 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 354 377 2.2E-18
Gene3D G3DSA:3.20.70.20 - - - 6 652 0.0
PANTHER PTHR43371 VITAMIN B12-DEPENDENT RIBONUCLEOTIDE REDUCTASE - - 10 705 0.0
Pfam PF02867 Ribonucleotide reductase, barrel domain IPR000788 Ribonucleotide reductase large subunit, C-terminal 103 649 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 177 196 2.2E-18
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 420 443 2.2E-18

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.