Pseudomonas sp. TKP, U771_24575

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00317
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00317
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00317
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG psk01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides biosynthesis from CTP InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG psk00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides <i>de novo</i> biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides <i>de novo</i> biosynthesis IV InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc adenosine deoxyribonucleotides <i>de novo</i> biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG psk00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc guanosine deoxyribonucleotides <i>de novo</i> biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc guanosine deoxyribonucleotides <i>de novo</i> biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc adenosine deoxyribonucleotides <i>de novo</i> biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides <i>de novo</i> biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR02506 JCVI: ribonucleoside-diphosphate reductase subunit alpha IPR013346 Ribonucleotide reductase, class I, alpha subunit, C-terminal 298 909 0.0
MobiDBLite mobidb-lite consensus disorder prediction - - 1 22 -
Pfam PF00317 Ribonucleotide reductase, all-alpha domain IPR013509 Ribonucleotide reductase large subunit, N-terminal 295 366 4.1E-22
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 583 594 7.2E-47
Pfam PF03477 ATP cone domain IPR005144 ATP-cone domain 33 129 1.8E-18
Gene3D G3DSA:3.20.70.20 - - - 221 917 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 447 466 7.2E-47
Pfam PF03477 ATP cone domain IPR005144 ATP-cone domain 151 234 7.6E-6
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 762 789 7.2E-47
CDD cd01679 RNR_I - - 320 909 0.0
Pfam PF02867 Ribonucleotide reductase, barrel domain IPR000788 Ribonucleotide reductase large subunit, C-terminal 372 908 0.0
SUPERFAMILY SSF51998 PFL-like glycyl radical enzymes - - 371 909 0.0
SUPERFAMILY SSF48168 R1 subunit of ribonucleotide reductase, N-terminal domain IPR008926 Ribonucleotide reductase R1 subunit, N-terminal 155 370 2.75E-62
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 686 709 7.2E-47
FunFam G3DSA:3.20.70.20:FF:000009 Ribonucleoside-diphosphate reductase - - 220 917 0.0
PANTHER PTHR11573 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN IPR039718 Ribonucleoside-diphosphate reductase large subunit 153 965 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 658 680 7.2E-47
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 620 643 7.2E-47

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.