Pseudomonas sp. TKP, U771_23845

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003911 DNA ligase (NAD+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00532
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00278
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03119
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03119
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG psk03030 DNA replication 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psk03410 Base excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psk03420 Nucleotide excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psk03430 Mismatch repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Coils Coil Coil - - 35 55 -
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 531 550 140.0
Pfam PF01653 NAD-dependent DNA ligase adenylation domain IPR013839 NAD-dependent DNA ligase, adenylation 4 324 3.2E-126
FunFam G3DSA:2.40.50.140:FF:000012 DNA ligase - - 324 397 1.1E-34
Gene3D G3DSA:3.40.50.10190 BRCT domain IPR036420 BRCT domain superfamily 696 782 1.4E-21
Gene3D G3DSA:1.10.150.20 - - - 449 523 1.5E-27
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 1 623 0.0
FunFam G3DSA:1.10.150.20:FF:000007 DNA ligase - - 449 524 1.1E-29
Pfam PF14520 Helix-hairpin-helix domain - - 465 519 0.0041
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 499 518 2000.0
Pfam PF00533 BRCA1 C Terminus (BRCT) domain IPR001357 BRCT domain 709 777 1.6E-8
FunFam G3DSA:3.30.470.30:FF:000001 DNA ligase - - 65 322 9.1E-107
Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type 415 453 1.6E-10
Gene3D G3DSA:1.10.287.610 Helix hairpin bin - - 1 64 4.5E-28
Gene3D G3DSA:3.30.470.30 DNA ligase/mRNA capping enzyme - - 65 322 3.2E-99
Hamap MF_01588 DNA ligase [ligA]. IPR001679 NAD-dependent DNA ligase 2 781 50.793205
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 612 785 1.1E-26
CDD cd00114 LIGANc IPR013839 NAD-dependent DNA ligase, adenylation 6 324 0.0
SUPERFAMILY SSF56091 DNA ligase/mRNA capping enzyme, catalytic domain - - 3 323 2.16E-117
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 465 484 4.0
PANTHER PTHR23389 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 - - 17 762 4.5E-47
SMART SM00532 ligaN3 IPR013840 NAD-dependent DNA ligase, N-terminal 3 467 0.0
SUPERFAMILY SSF52113 BRCT domain IPR036420 BRCT domain superfamily 710 781 1.25E-15
Gene3D G3DSA:1.10.150.20 - - - 622 678 1.9E-8
SMART SM00292 BRCT_7 IPR001357 BRCT domain 707 784 1.1E-5
Pfam PF03120 NAD-dependent DNA ligase OB-fold domain IPR004150 NAD-dependent DNA ligase, OB-fold 329 405 6.2E-35
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 613 699 7.78E-12
FunFam G3DSA:1.10.287.610:FF:000002 DNA ligase - - 1 64 9.9E-29
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 411 597 4.08E-50
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 326 406 3.6E-28
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 324 397 6.7E-33
NCBIfam TIGR00575 JCVI: DNA ligase (NAD(+)) LigA IPR001679 NAD-dependent DNA ligase 11 595 0.0
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 529 592 1.5E-18
Gene3D G3DSA:6.20.10.30 - - - 398 448 1.0E-12
CDD cd17748 BRCT_DNA_ligase_like - - 711 777 1.66242E-22
Gene3D G3DSA:1.10.150.20 - - - 524 606 4.0E-21

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.