Pseudomonas aeruginosa MTB-1, U769_28445
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0008460 | dTDP-glucose 4,6-dehydratase activity |
Inferred from Sequence Model
Term mapped from: InterPro:cd05246
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0009225 | nucleotide-sugar metabolic process |
Inferred from Sequence Model
Term mapped from: InterPro:cd05246
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
|
|
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | paem00523 | Polyketide sugar unit biosynthesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | paem00525 | Acarbose and validamycin biosynthesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | paem00521 | Streptomycin biosynthesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | paem01100 | Metabolic pathways | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | paem01130 | Biosynthesis of antibiotics | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Pfam | PF16363 | GDP-mannose 4,6 dehydratase | IPR016040 | NAD(P)-binding domain | 4 | 324 | 9.8E-102 |
| Gene3D | G3DSA:3.40.50.720 | - | - | - | 3 | 322 | 0.0 |
| CDD | cd05246 | dTDP_GD_SDR_e | IPR005888 | dTDP-glucose 4,6-dehydratase | 1 | 333 | 0.0 |
| Gene3D | G3DSA:3.90.25.10 | - | - | - | 200 | 332 | 0.0 |
| PANTHER | PTHR43000 | DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED | - | - | 2 | 343 | 5.7E-108 |
| NCBIfam | TIGR01181 | JCVI: dTDP-glucose 4,6-dehydratase | IPR005888 | dTDP-glucose 4,6-dehydratase | 3 | 337 | 0.0 |
| SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | IPR036291 | NAD(P)-binding domain superfamily | 1 | 335 | 1.42E-89 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.