Pseudomonas aeruginosa PAO1, PA5378 (cbcX)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Cellular Component	GO:0043190	ATP-binding cassette (ABC) transporter complex	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Biological Process	GO:0015871	choline transport	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	19919675	Reviewed by curator
Biological Process	GO:0042426	choline catabolic process	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	21478341	Reviewed by curator
Biological Process	GO:1902603	carnitine transmembrane transport	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	21478341	Reviewed by curator
Biological Process	GO:0031460	glycine betaine transport	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	21478341	Reviewed by curator
Molecular Function	GO:0033265	choline binding	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Biological Process	GO:0031457	glycine betaine catabolic process	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Biological Process	GO:0042426	choline catabolic process	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Molecular Function	GO:0005275	amine transmembrane transporter activity	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Biological Process	GO:0015838	amino-acid betaine transport	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Biological Process	GO:0031460	glycine betaine transport	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Molecular Function	GO:0022857	transmembrane transporter activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF04069	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0055085	transmembrane transport	ISM Inferred from Sequence Model Term mapped from: InterPro:PF04069	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0015871	choline transport	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR03414	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0033265	choline binding	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR03414	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Cellular Component	GO:0042597	periplasmic space	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR03414	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Cellular Component	GO:0043190	ATP-binding cassette (ABC) transporter complex	ISM Inferred from Sequence Model Term mapped from: InterPro:PF04069	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transport of small molecules Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae02010	ABC transporters	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
NCBIfam	TIGR03414	JCVI: choline ABC transporter substrate-binding protein	IPR017783	Choline ABC transporter, substrate-binding protein	21	307	0.0
Gene3D	G3DSA:3.40.190.10	-	-	-	30	291	9.0E-116
CDD	cd13640	PBP2_ChoX	IPR017783	Choline ABC transporter, substrate-binding protein	30	294	0.0
Gene3D	G3DSA:3.40.190.100	-	-	-	111	220	9.0E-116
Pfam	PF04069	Substrate binding domain of ABC-type glycine betaine transport system	IPR007210	ABC-type glycine betaine transport system, substrate-binding domain	29	281	1.1E-63
FunFam	G3DSA:3.40.190.100:FF:000002	Choline ABC transporter substrate-binding protein	-	-	111	220	7.4E-62
SUPERFAMILY	SSF53850	Periplasmic binding protein-like II	-	-	21	298	3.53E-92

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.