Pseudomonas aeruginosa PAO1, PA5345 (recG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0034644 cellular response to UV
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 10913087 Reviewed by curator
Biological Process GO:0071247 cellular response to chromate
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 16105671 Reviewed by curator
Molecular Function GO:0003678 DNA helicase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 22621928 Reviewed by curator
Biological Process GO:0072715 cellular response to selenite ion
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 16105671 Reviewed by curator
Biological Process GO:0034599 cellular response to oxidative stress
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 10913087 Reviewed by curator
Molecular Function GO:0000976 transcription regulatory region sequence-specific DNA binding
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 22621928 Reviewed by curator
Biological Process GO:0006281 DNA repair
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 10913087 Reviewed by curator
Molecular Function GO:0009378 four-way junction helicase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 22621928 Reviewed by curator
Biological Process GO:0006281 DNA repair
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 16105671 Reviewed by curator
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00270
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00270
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003678 DNA helicase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00643
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006310 DNA recombination
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00643
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00643
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other PAO1 genes in this class
Transcriptional regulators Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae03440 Homologous recombination 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR00643 JCVI: ATP-dependent DNA helicase RecG IPR004609 ATP-dependent DNA helicase RecG 27 663 0.0
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 456 628 3.4E-54
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 7 172 2.06E-35
SMART SM00490 helicmild6 IPR001650 Helicase, C-terminal 503 587 1.1E-21
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 317 598 3.02E-53
Pfam PF17191 RecG wedge domain IPR033454 RecG, wedge domain 12 170 4.0E-14
FunFam G3DSA:3.40.50.300:FF:000391 ATP-dependent DNA helicase RecG - - 456 628 4.1E-92
Pfam PF00270 DEAD/DEAH box helicase IPR011545 DEAD/DEAH box helicase domain 293 430 9.7E-18
SMART SM00487 ultradead3 IPR014001 Helicase superfamily 1/2, ATP-binding domain 265 458 5.7E-26
CDD cd04488 RecG_wedge_OBF - - 61 134 2.5797E-22
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 208 448 3.6E-79
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 45 138 2.4E-9
FunFam G3DSA:2.40.50.140:FF:000351 ATP-dependent DNA helicase RecG - - 45 138 7.0E-61
Pfam PF00271 Helicase conserved C-terminal domain IPR001650 Helicase, C-terminal 479 586 7.1E-16
PANTHER PTHR47964 ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC IPR047112 ATP-dependent DNA helicase RecG/Transcription-repair-coupling factor 8 671 0.0
CDD cd17992 DEXHc_RecG - - 224 451 1.96864E-113
Pfam PF19833 ATP-dependent DNA helicase RecG, domain 3, C-terminal IPR045562 ATP-dependent DNA helicase RecG, domain 3, C-terminal 614 675 1.6E-13

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.