Pseudomonas aeruginosa PAO1, PA5324 (sphR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0051872 sphingosine catabolic process
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 24465209 Reviewed by curator
Biological Process GO:0051872 sphingosine catabolic process
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 24465209 Reviewed by curator
Molecular Function GO:0000976 transcription regulatory region sequence-specific DNA binding
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 24465209 Reviewed by curator
Molecular Function GO:0046625 sphingolipid binding
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 24465209 Reviewed by curator
Molecular Function GO:0003700 DNA-binding transcription factor activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00342
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00342
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0043565 sequence-specific DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00342
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Adaptation, Protection Other PAO1 genes in this class
Transcriptional regulators Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR47894 HTH-TYPE TRANSCRIPTIONAL REGULATOR GADX - - 13 342 1.9E-92
SMART SM00342 aracneu4 IPR018060 DNA binding HTH domain, AraC-type 257 339 5.5E-20
Pfam PF12833 Helix-turn-helix domain IPR018060 DNA binding HTH domain, AraC-type 264 340 2.1E-19
SUPERFAMILY SSF46689 Homeodomain-like IPR009057 Homeobox-like domain superfamily 292 341 6.27E-11
Gene3D G3DSA:1.10.10.60 - - - 236 345 3.5E-24
Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal 31 214 1.5E-35

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.