Pseudomonas aeruginosa PAO1, PA5295 (proE)

Annotation Updates

Date	Description	Acknowledgements
Jan 24, 2007	New evidence reference (PMID): 16477007. Deleting structue feature: PF00563: Domain of unknown function 2. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). Deleting structue feature: PF00990: Domain of unknown function. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases.	Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Sep 15, 2020	New gene name: proE. New product name: ProE. New product name synonym: phosphodiesterase regulator of EPS. New product name confidence: Class 1. New comment: Mutation of proE results in wrinkly colony morphology in P. aeruginosa PAO1 (PMID:32582123);ProE negatively regulates the transcriptional expression of pel and psl (PMID:32582123). New PMID: 32582123.	Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada