Pseudomonas aeruginosa PAO1, PA5166 (dctD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000156 phosphorelay response regulator activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 21725012 Reviewed by curator
Biological Process GO:0032892 positive regulation of organic acid transport
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 21725012 Reviewed by curator
Molecular Function GO:0043565 sequence-specific DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01590
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00382
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00448
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008134 transcription factor binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF18024
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PAO1 genes in this class
Transcriptional regulators Other PAO1 genes in this class
Transport of small molecules Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Two-component System ECO:0000037
not_recorded
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00009 AAA - - 157 322 2.65862E-22
CDD cd17549 REC_DctD-like - - 13 142 6.04909E-75
PRINTS PR01590 FIS bacterial regulatory protein HTH signature IPR002197 DNA binding HTH domain, Fis-type 412 429 5.8E-5
Gene3D G3DSA:1.10.8.60 - - - 323 399 6.7E-20
FunFam G3DSA:3.40.50.2300:FF:000018 DNA-binding transcriptional regulator NtrC - - 9 140 5.9E-47
Pfam PF18024 Helix-turn-helix domain IPR030828 TyrR family, helix-turn-helix domain 402 448 7.4E-7
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 141 322 1.0E-62
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 152 381 6.84E-67
Gene3D G3DSA:3.40.50.2300 - - - 11 130 8.3E-33
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 13 122 8.6E-29
SMART SM00382 AAA_5 IPR003593 AAA+ ATPase domain 172 315 1.9E-9
PRINTS PR01590 FIS bacterial regulatory protein HTH signature IPR002197 DNA binding HTH domain, Fis-type 429 449 5.8E-5
FunFam G3DSA:3.40.50.300:FF:000006 DNA-binding transcriptional regulator NtrC - - 144 322 7.1E-73
PANTHER PTHR32071 TRANSCRIPTIONAL REGULATORY PROTEIN - - 10 449 4.5E-130
SUPERFAMILY SSF46689 Homeodomain-like IPR009057 Homeobox-like domain superfamily 397 448 1.79E-9
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 11 122 4.4E-32
Pfam PF00158 Sigma-54 interaction domain IPR002078 RNA polymerase sigma factor 54 interaction domain 152 318 1.4E-66
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 12 197 1.08E-42
Gene3D G3DSA:1.10.10.60 - - - 400 450 1.2E-9

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.