Pseudomonas aeruginosa PAO1, PA5112 (estA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0071973 bacterial-type flagellum-dependent cell motility
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 17631636 Reviewed by curator
Molecular Function GO:0052689 carboxylic ester hydrolase activity
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 17631636 Reviewed by curator
Biological Process GO:0044010 single-species biofilm formation
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 17631636 Reviewed by curator
Biological Process GO:0009247 glycolipid biosynthetic process
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 17631636 Reviewed by curator
Biological Process GO:0071978 bacterial-type flagellum-dependent swarming motility
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 20360178 Reviewed by curator
Molecular Function GO:0016788 hydrolase activity, acting on ester bonds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00657
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Secreted Factors (toxins, enzymes, alginate) Other PAO1 genes in this class
Fatty acid and phospholipid metabolism Other PAO1 genes in this class
Protein secretion/export apparatus Other PAO1 genes in this class
Motility & Attachment Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Type V secretion system ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00869 Autotransporter_2 IPR005546 Autotransporter beta-domain 370 636 1.9E-36
PANTHER PTHR45642 GDSL ESTERASE/LIPASE EXL3 - - 29 325 1.6E-16
FunFam G3DSA:2.40.128.130:FF:000004 Autotransporter domain-containing esterase - - 339 646 0.0
SUPERFAMILY SSF103515 Autotransporter IPR036709 Autotransporter beta-domain superfamily 349 646 5.36E-47
Pfam PF00657 GDSL-like Lipase/Acylhydrolase IPR001087 GDSL lipase/esterase 32 325 1.2E-17
CDD cd01847 Triacylglycerol_lipase_like - - 29 330 2.41574E-58
Pfam PF03797 Autotransporter beta-domain IPR005546 Autotransporter beta-domain 374 626 5.5E-48
FunFam G3DSA:3.40.50.1110:FF:000027 Esterase EstA - - 19 338 0.0
Gene3D G3DSA:3.40.50.1110 SGNH hydrolase IPR036514 SGNH hydrolase superfamily 19 338 6.7E-94
Gene3D G3DSA:2.40.128.130 - IPR036709 Autotransporter beta-domain superfamily 339 646 4.8E-84
PIRSF PIRSF037375 EstA IPR017186 Lipase, autotransporter EstA 2 646 0.0
NCBIfam NF041609 NCBIFAM: esterase EstP IPR048099 Esterase EstA/EstP 4 646 0.0
SUPERFAMILY SSF52266 SGNH hydrolase - - 30 330 1.53E-15

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.