Pseudomonas aeruginosa PAO1, PA5035 (gltD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006537 glutamate biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 4565085 Reviewed by curator
Molecular Function GO:0004355 glutamate synthase (NADPH) activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 4565085 Reviewed by curator
Molecular Function GO:0051536 iron-sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.1060.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051539 4 iron, 4 sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01318
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07992
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00250 Alanine, aspartate and glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc AMMASSIM-PWY ammonia assimilation cycle III 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc GLUTAMOLYSIS-PWY glutamate degradation III 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Nitrogen metabolism ECO:0000037
not_recorded
PseudoCyc GLUTAMINEFUM-PWY L-glutamine degradation II 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00910 Nitrogen metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Glutamate metabolism ECO:0000037
not_recorded
PseudoCyc GLUTSYN-PWY L-glutamate biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster IPR028261 Dihydroprymidine dehydrogenase domain II 33 142 2.1E-37
PRINTS PR00419 Adrenodoxin reductase family signature - - 331 344 7.9E-36
PRINTS PR00419 Adrenodoxin reductase family signature - - 297 311 7.9E-36
Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase IPR023753 FAD/NAD(P)-binding domain 156 464 7.5E-25
Gene3D G3DSA:3.40.50.720 - - - 153 260 6.9E-18
SUPERFAMILY SSF46548 alpha-helical ferredoxin - - 15 165 9.94E-39
PRINTS PR00419 Adrenodoxin reductase family signature - - 156 178 7.9E-36
PRINTS PR00419 Adrenodoxin reductase family signature - - 179 192 7.9E-36
PANTHER PTHR42783 GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN - - 12 476 0.0
Coils Coil Coil - - 325 345 -
FunFam G3DSA:1.10.1060.10:FF:000004 Glutamate synthase, small subunit - - 17 153 5.1E-73
Gene3D G3DSA:3.50.50.60 - IPR036188 FAD/NAD(P)-binding domain superfamily 261 405 3.2E-44
SUPERFAMILY SSF51971 Nucleotide-binding domain - - 153 406 2.0E-70
FunFam G3DSA:3.50.50.60:FF:000041 Glutamate synthase, small subunit - - 261 405 2.9E-85
NCBIfam TIGR01318 JCVI: glutamate synthase, small subunit IPR006006 Glutamate synthase NADPH small chain-like 14 477 0.0
Gene3D G3DSA:1.10.1060.10 - IPR009051 Alpha-helical ferredoxin 15 152 2.7E-38
PRINTS PR00419 Adrenodoxin reductase family signature - - 221 231 7.9E-36

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.