Pseudomonas aeruginosa PAO1, PA4976 (aruH)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0008483	transaminase activity	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	17416668	Reviewed by curator
Biological Process	GO:0006527	arginine catabolic process	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	17416668	Reviewed by curator
Biological Process	GO:0009058	biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00155	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0030170	pyridoxal phosphate binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00155	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCAP		Tyrosine metabolism		ECO:0000037 not_recorded
PseudoCAP		Glutamate metabolism		ECO:0000037 not_recorded
PseudoCyc	ASPASN-PWY	superpathway of L-aspartate and L-asparagine biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCyc	GLUTDEG-PWY	L-glutamate degradation II	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCAP		Arginine and proline metabolism		ECO:0000037 not_recorded
PseudoCyc	ASPARTATESYN-PWY	L-aspartate biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCyc	ASPBIO-PWY	aspartate biosynthesis II	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCyc	PWY-5742	L-arginine degradation IX (arginine:pyruvate transaminase pathway)	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Phenylalanine, tyrosine and tryptophan biosynthesis		ECO:0000037 not_recorded
PseudoCAP		Phenylalanine metabolism		ECO:0000037 not_recorded
PseudoCAP		Alanine and Aspartate metabolism		ECO:0000037 not_recorded
PseudoCyc	MALATE-ASPARTATE-SHUTTLE-PWY	L-aspartate degradation II	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCyc	THRESYN-PWY	superpathway of L-threonine biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae00330	Arginine and proline metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	P4-PWY	superpathway of L-lysine, L-threonine and L-methionine biosynthesis I	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
CDD	cd00609	AAT_like	-	-	37	383	4.9695E-115
SUPERFAMILY	SSF53383	PLP-dependent transferases	IPR015424	Pyridoxal phosphate-dependent transferase	15	383	1.22E-111
Pfam	PF00155	Aminotransferase class I and II	IPR004839	Aminotransferase, class I/classII	33	382	1.9E-71
Gene3D	G3DSA:3.90.1150.10	Aspartate Aminotransferase, domain 1	IPR015422	Pyridoxal phosphate-dependent transferase, small domain	29	382	1.8E-118
PANTHER	PTHR46383	ASPARTATE AMINOTRANSFERASE	-	-	17	388	2.2E-113
FunFam	G3DSA:3.40.640.10:FF:000033	Aspartate aminotransferase	-	-	64	284	5.5E-80
Gene3D	G3DSA:3.40.640.10	-	IPR015421	Pyridoxal phosphate-dependent transferase, major domain	64	284	1.8E-118

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.