Pseudomonas aeruginosa PAO1, PA4740 (pnp)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0016070 RNA metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0004654 polyribonucleotide nucleotidyltransferase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 13438894 Reviewed by curator
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00575
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003723 RNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR03591
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004654 polyribonucleotide nucleotidyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR03591
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006396 RNA processing
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03726
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006402 mRNA catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR03591
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcription, RNA processing and degradation Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Pyrimidine metabolism ECO:0000037
not_recorded
KEGG pae00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Purine metabolism ECO:0000037
not_recorded
KEGG pae03018 RNA degradation 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00316 S1_6 IPR022967 RNA-binding domain, S1 621 691 8.9E-25
Pfam PF00575 S1 RNA binding domain IPR003029 S1 domain 620 691 9.6E-18
FunFam G3DSA:3.30.230.70:FF:000001 Polyribonucleotide nucleotidyltransferase - - 2 234 1.1E-106
PIRSF PIRSF005499 PNPase IPR012162 Polyribonucleotide nucleotidyltransferase 1 700 0.0
CDD cd02393 KH-I_PNPase - - 552 621 2.61457E-27
NCBIfam TIGR03591 JCVI: polyribonucleotide nucleotidyltransferase IPR012162 Polyribonucleotide nucleotidyltransferase 9 692 0.0
SUPERFAMILY SSF54791 Eukaryotic type KH-domain (KH-domain type I) IPR036612 K Homology domain, type 1 superfamily 556 641 7.01E-24
Pfam PF01138 3' exoribonuclease family, domain 1 IPR001247 Exoribonuclease, phosphorolytic domain 1 15 143 4.6E-21
CDD cd11363 RNase_PH_PNPase_1 - - 5 233 2.61765E-125
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 623 694 1.1E-26
SUPERFAMILY SSF55666 Ribonuclease PH domain 2-like IPR036345 Exoribonuclease, PH domain 2 superfamily 451 550 4.49E-29
SUPERFAMILY SSF54211 Ribosomal protein S5 domain 2-like IPR020568 Ribosomal protein uS5 domain 2-type superfamily 293 489 1.92E-49
Gene3D G3DSA:3.30.230.70 - IPR027408 PNPase/RNase PH domain superfamily 235 550 0.0
CDD cd11364 RNase_PH_PNPase_2 - - 324 545 0.0
FunFam G3DSA:3.30.1370.10:FF:000001 Polyribonucleotide nucleotidyltransferase - - 551 619 1.6E-24
Pfam PF03725 3' exoribonuclease family, domain 2 IPR015847 Exoribonuclease, phosphorolytic domain 2 146 210 1.3E-11
FunFam G3DSA:3.30.230.70:FF:000002 Polyribonucleotide nucleotidyltransferase - - 236 550 0.0
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 615 693 1.94E-22
FunFam G3DSA:2.40.50.140:FF:000023 Polyribonucleotide nucleotidyltransferase - - 623 693 1.2E-33
Pfam PF03725 3' exoribonuclease family, domain 2 IPR015847 Exoribonuclease, phosphorolytic domain 2 460 529 9.3E-6
SUPERFAMILY SSF54211 Ribosomal protein S5 domain 2-like IPR020568 Ribosomal protein uS5 domain 2-type superfamily 3 143 3.44E-50
Pfam PF01138 3' exoribonuclease family, domain 1 IPR001247 Exoribonuclease, phosphorolytic domain 1 325 457 2.0E-22
SMART SM00322 kh_6 IPR004087 K Homology domain 553 618 2.4E-13
SUPERFAMILY SSF55666 Ribonuclease PH domain 2-like IPR036345 Exoribonuclease, PH domain 2 superfamily 144 235 8.41E-27
Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. IPR012162 Polyribonucleotide nucleotidyltransferase 2 694 30.535915
Pfam PF00013 KH domain IPR004088 K Homology domain, type 1 558 613 5.0E-12
CDD cd04472 S1_PNPase - - 623 690 7.10356E-35
Gene3D G3DSA:3.30.230.70 - IPR027408 PNPase/RNase PH domain superfamily 1 234 2.0E-86
Gene3D G3DSA:3.30.1370.10 K Homology domain, type 1 IPR036612 K Homology domain, type 1 superfamily 551 622 1.0E-28
Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain 242 321 7.0E-23
PANTHER PTHR11252 POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE IPR012162 Polyribonucleotide nucleotidyltransferase 2 695 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.