Pseudomonas aeruginosa PAO1, PA3834 (valS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0009098 leucine biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0009909 regulation of flower development
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0044267 cellular protein metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0009097 isoleucine biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0043039 tRNA aminoacylation
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.740.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004832 valine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02004
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006438 valyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02004
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF10458
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0002161 aminoacyl-tRNA editing activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.740.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02004
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02004
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00133
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Translation, post-translational modification, degradation Other PAO1 genes in this class
Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Valine, leucine and isoleucine biosynthesis ECO:0000037
not_recorded
KEGG pae00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Aminoacyl-tRNA biosynthesis ECO:0000037
not_recorded
PseudoCyc TRNA-CHARGING-PWY tRNA charging 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 327 552 2.0E-74
Pfam PF10458 Valyl tRNA synthetase tRNA binding arm IPR019499 Valyl-tRNA synthetase, tRNA-binding arm 886 947 4.2E-19
PRINTS PR00986 Valyl-tRNA synthetase signature IPR002303 Valine-tRNA ligase 366 379 1.1E-35
FunFam G3DSA:3.40.50.620:FF:000146 Valine--tRNA ligase - - 328 552 0.0
NCBIfam TIGR00422 JCVI: valine--tRNA ligase IPR002303 Valine-tRNA ligase 1 930 0.0
Gene3D G3DSA:3.90.740.10 - IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain 240 310 1.5E-9
FunFam G3DSA:3.90.740.10:FF:000003 Valine--tRNA ligase - - 198 238 5.7E-23
Gene3D G3DSA:1.10.287.380 - IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily 876 947 3.3E-24
SUPERFAMILY SSF52374 Nucleotidylyl transferase - - 1 638 0.0
PRINTS PR00986 Valyl-tRNA synthetase signature IPR002303 Valine-tRNA ligase 233 250 1.1E-35
PRINTS PR00986 Valyl-tRNA synthetase signature IPR002303 Valine-tRNA ligase 466 487 1.1E-35
PRINTS PR00986 Valyl-tRNA synthetase signature IPR002303 Valine-tRNA ligase 33 44 1.1E-35
Coils Coil Coil - - 923 950 -
SUPERFAMILY SSF46589 tRNA-binding arm IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm 883 947 9.94E-18
Coils Coil Coil - - 881 908 -
CDD cd07962 Anticodon_Ia_Val IPR033705 Valyl tRNA synthetase, anticodon-binding domain 627 764 1.28015E-65
FunFam G3DSA:1.10.730.10:FF:000007 Valine--tRNA ligase - - 575 816 2.3E-121
PANTHER PTHR11946 VALYL-TRNA SYNTHETASES IPR002303 Valine-tRNA ligase 1 945 0.0
Hamap MF_02004 Valine--tRNA ligase [valS]. IPR002303 Valine-tRNA ligase 1 948 16.171726
SUPERFAMILY SSF50677 ValRS/IleRS/LeuRS editing domain IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain 188 362 2.35E-59
Gene3D G3DSA:3.90.740.10 - IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain 203 239 2.6E-5
CDD cd00817 ValRS_core - - 32 627 0.0
PRINTS PR00986 Valyl-tRNA synthetase signature IPR002303 Valine-tRNA ligase 497 515 1.1E-35
Pfam PF08264 Anticodon-binding domain of tRNA ligase IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding 671 823 9.2E-44
FunFam G3DSA:1.10.287.380:FF:000001 Valine--tRNA ligase - - 876 947 6.9E-25
FunFam G3DSA:3.40.50.620:FF:000020 Valine--tRNA ligase, mitochondrial - - 3 198 3.2E-98
Pfam PF00133 tRNA synthetases class I (I, L, M and V) IPR002300 Aminoacyl-tRNA synthetase, class Ia 14 628 0.0
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 3 202 3.6E-64
Gene3D G3DSA:1.10.730.10 - - - 576 816 4.3E-74
SUPERFAMILY SSF47323 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding 639 898 1.23E-70

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.