Pseudomonas aeruginosa PAO1, PA3345 (hptB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0050921 positive regulation of chemotaxis
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 16182517 Reviewed by curator
Biological Process GO:2000145 regulation of cell motility
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 16182517 Reviewed by curator
Molecular Function GO:0009927 histidine phosphotransfer kinase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 16182517 Reviewed by curator
Biological Process GO:1900191 negative regulation of single-species biofilm formation
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 16182517 Reviewed by curator
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00088
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Motility & Attachment Other PAO1 genes in this class
Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 25 100 1.4E-14
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 25 100 7.22618E-7
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 3 113 8.24E-26
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1 110 3.1E-24

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.