Pseudomonas aeruginosa PAO1, PA2907 (cobL)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0051188	obsolete cofactor biosynthetic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0009236	cobalamin biosynthetic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	1732195	Reviewed by curator
Biological Process	GO:0009236	cobalamin biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR02469	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF53335	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0008168	methyltransferase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00590	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0008276	protein methyltransferase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR02469	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae00860	Porphyrin and chlorophyll metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	P381-PWY	adenosylcobalamin biosynthesis II (late cobalt incorporation)	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCyc	PWY-7376	cob(II)yrinate a,c-diamide biosynthesis II (late cobalt incorporation)	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCAP		Cobalamin biosynthesis		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Gene3D	G3DSA:3.40.50.150	Vaccinia Virus protein VP39	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily	219	410	8.4E-61
SUPERFAMILY	SSF53335	S-adenosyl-L-methionine-dependent methyltransferases	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily	211	385	4.66E-30
NCBIfam	TIGR02467	JCVI: precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE	IPR012818	Precorrin-6Y methyltransferase	13	198	2.2E-41
SUPERFAMILY	SSF53790	Tetrapyrrole methylase	IPR035996	Tetrapyrrole methylase superfamily	10	210	2.88E-36
PANTHER	PTHR43182	COBALT-PRECORRIN-6B C(15)-METHYLTRANSFERASE (DECARBOXYLATING)	-	-	9	406	0.0
NCBIfam	TIGR02469	JCVI: precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT	IPR014008	Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit	236	357	1.4E-34
Pfam	PF00590	Tetrapyrrole (Corrin/Porphyrin) Methylases	IPR000878	Tetrapyrrole methylase	11	191	9.2E-17
Gene3D	G3DSA:3.40.1010.10	-	IPR014777	Tetrapyrrole methylase, subdomain 1	10	108	1.6E-11
CDD	cd11644	Precorrin-6Y-MT	IPR012818	Precorrin-6Y methyltransferase	14	210	1.08457E-62
CDD	cd02440	AdoMet_MTases	-	-	258	352	4.45208E-8
PIRSF	PIRSF036428	CobL_MTase	IPR006365	Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase	7	407	0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.