Pseudomonas aeruginosa PAO1, PA2532 (tpx)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0050896 response to stimulus
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0070301 cellular response to hydrogen peroxide
IMP
Inferred from Mutant Phenotype 		ECO:0000016
loss-of-function mutant phenotype evidence		 22609922 Reviewed by curator
Molecular Function GO:0008379 thioredoxin peroxidase activity
IDA
Inferred from Direct Assay 		ECO:0000005
enzyme assay evidence		 22609922 Reviewed by curator
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF08534
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016209 antioxidant activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00269
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008379 thioredoxin peroxidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00269
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Adaptation, Protection Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.40.30.10:FF:000056 Thiol peroxidase - - 1 165 9.5E-88
Hamap MF_00269 Thiol peroxidase [tpx]. IPR002065 Thiol peroxidase Tpx 3 165 38.273071
Gene3D G3DSA:3.40.30.10 Glutaredoxin - - 1 165 2.8E-57
Pfam PF08534 Redoxin IPR013740 Redoxin 19 162 5.2E-28
CDD cd03014 PRX_Atyp2cys IPR002065 Thiol peroxidase Tpx 19 164 6.50214E-75
SUPERFAMILY SSF52833 Thioredoxin-like IPR036249 Thioredoxin-like superfamily 1 163 1.64E-42
PANTHER PTHR43110 THIOL PEROXIDASE - - 1 165 2.4E-59

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.