Pseudomonas aeruginosa PAO1, PA2494 (mexF)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0046677 | response to antibiotic | Inferred from Direct Assay | ECO:0000002 direct assay evidence |
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| Cellular Component | GO:0016020 | membrane | Inferred from Direct Assay | ECO:0000002 direct assay evidence |
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| Biological Process | GO:0006811 | ion transport | Inferred from Sequence or Structural Similarity | ECO:0000250 sequence similarity evidence used in manual assertion |
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| Biological Process | GO:0006810 | transport | Inferred from Direct Assay | ECO:0000002 direct assay evidence |
||
| Molecular Function | GO:0042910 | xenobiotic transmembrane transporter activity | Inferred from Direct Assay | ECO:0000314 direct assay evidence used in manual assertion |
9044268 | Reviewed by curator |
| Molecular Function | GO:0015562 | efflux transmembrane transporter activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00915
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
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| Biological Process | GO:0055085 | transmembrane transport |
Inferred from Sequence Model
Term mapped from: InterPro:PR00702
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Cellular Component | GO:0016020 | membrane |
Inferred from Sequence Model
Term mapped from: InterPro:PR00702
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0022857 | transmembrane transporter activity |
Inferred from Sequence Model
Term mapped from: InterPro:PR00702
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0042908 | xenobiotic transport |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00915
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| FunFam | G3DSA:3.30.70.1430:FF:000001 | Efflux pump membrane transporter | - | - | 40 | 143 | 1.0E-33 |
| NCBIfam | TIGR00915 | JCVI: efflux RND transporter permease subunit | IPR004764 | Multidrug resistance protein MdtF-like | 3 | 1051 | 0.0 |
| PRINTS | PR00702 | Acriflavin resistance protein family signature | IPR001036 | Acriflavin resistance protein | 447 | 470 | 3.4E-94 |
| Gene3D | G3DSA:3.30.70.1440 | Multidrug efflux transporter AcrB pore domain | - | - | 683 | 884 | 0.0 |
| SUPERFAMILY | SSF82714 | Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | IPR027463 | Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains | 185 | 274 | 8.37E-21 |
| FunFam | G3DSA:1.20.1640.10:FF:000001 | Efflux pump membrane transporter | - | - | 324 | 510 | 1.9E-73 |
| SUPERFAMILY | SSF82693 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | - | - | 138 | 333 | 2.2E-28 |
| PANTHER | PTHR32063 | - | IPR001036 | Acriflavin resistance protein | 1 | 1050 | 0.0 |
| Gene3D | G3DSA:3.30.2090.10 | Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | IPR027463 | Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains | 737 | 825 | 0.0 |
| Gene3D | G3DSA:1.20.1640.10 | Multidrug efflux transporter AcrB transmembrane domain | - | - | 9 | 526 | 0.0 |
| PRINTS | PR00702 | Acriflavin resistance protein family signature | IPR001036 | Acriflavin resistance protein | 10 | 34 | 3.4E-94 |
| PRINTS | PR00702 | Acriflavin resistance protein family signature | IPR001036 | Acriflavin resistance protein | 472 | 495 | 3.4E-94 |
| SUPERFAMILY | SSF82693 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | - | - | 576 | 682 | 2.14E-27 |
| SUPERFAMILY | SSF82866 | Multidrug efflux transporter AcrB transmembrane domain | - | - | 844 | 1040 | 3.01E-46 |
| Gene3D | G3DSA:3.30.2090.10 | Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | IPR027463 | Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains | 183 | 281 | 0.0 |
| PRINTS | PR00702 | Acriflavin resistance protein family signature | IPR001036 | Acriflavin resistance protein | 38 | 56 | 3.4E-94 |
| SUPERFAMILY | SSF82693 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | - | - | 683 | 870 | 5.49E-25 |
| FunFam | G3DSA:3.30.2090.10:FF:000007 | Efflux pump membrane transporter | - | - | 737 | 825 | 4.7E-52 |
| PRINTS | PR00702 | Acriflavin resistance protein family signature | IPR001036 | Acriflavin resistance protein | 366 | 387 | 3.4E-94 |
| PRINTS | PR00702 | Acriflavin resistance protein family signature | IPR001036 | Acriflavin resistance protein | 563 | 580 | 3.4E-94 |
| SUPERFAMILY | SSF82714 | Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | IPR027463 | Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains | 735 | 820 | 2.35E-20 |
| FunFam | G3DSA:3.30.2090.10:FF:000001 | Efflux pump membrane transporter | - | - | 183 | 281 | 1.1E-39 |
| Gene3D | G3DSA:1.20.1640.10 | Multidrug efflux transporter AcrB transmembrane domain | - | - | 527 | 1037 | 0.0 |
| FunFam | G3DSA:3.30.70.1430:FF:000002 | Efflux pump membrane transporter | - | - | 581 | 682 | 8.3E-32 |
| SUPERFAMILY | SSF82693 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | - | - | 41 | 134 | 4.19E-25 |
| Gene3D | G3DSA:3.30.70.1320 | Multidrug efflux transporter AcrB pore domain like | - | - | 135 | 334 | 0.0 |
| PRINTS | PR00702 | Acriflavin resistance protein family signature | IPR001036 | Acriflavin resistance protein | 339 | 362 | 3.4E-94 |
| PRINTS | PR00702 | Acriflavin resistance protein family signature | IPR001036 | Acriflavin resistance protein | 394 | 418 | 3.4E-94 |
| Pfam | PF00873 | AcrB/AcrD/AcrF family | IPR001036 | Acriflavin resistance protein | 3 | 1040 | 0.0 |
| PRINTS | PR00702 | Acriflavin resistance protein family signature | IPR001036 | Acriflavin resistance protein | 632 | 646 | 3.4E-94 |
| Gene3D | G3DSA:3.30.70.1430 | Multidrug efflux transporter AcrB pore domain | - | - | 581 | 682 | 0.0 |
| SUPERFAMILY | SSF82866 | Multidrug efflux transporter AcrB transmembrane domain | - | - | 299 | 499 | 2.75E-50 |
| Gene3D | G3DSA:3.30.70.1430 | Multidrug efflux transporter AcrB pore domain | - | - | 40 | 833 | 0.0 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.