Pseudomonas aeruginosa PAO1, PA2392 (pvdP)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PAO1 (Stover et al., 2000) GCF_000006765.1|latest
Locus Tag	PA2392
Name	pvdP
Replicon	chromosome
Genomic location	2646776 - 2648410 (- strand)
Transposon Mutants	2 transposon mutants in PAO1
Transposon Mutants in orthologs	1 transposon mutants in orthologs

Cross-References

RefSeq	NP_251082.1
GI	15597588
Affymetrix	PA2392_at
Entrez	882224
GenBank	AAG05780.1
INSDC	AAG05780.1
NCBI Locus Tag	PA2392
protein_id(GenBank)	gb|AAG05780.1|AE004665_7|gnl|PseudoCAP|PA2392
TIGR	NTL03PA02392
UniParc	UPI00000C56AB
UniProtKB Acc	Q9I188
UniProtKB ID	Q9I188_PSEAE
UniRef100	UniRef100_Q9I188
UniRef50	UniRef50_Q4K9A0
UniRef90	UniRef90_Q9I188

Product

Feature Type	CDS
Coding Frame	1
Product Name	PvdP Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7)	-3.98
Kyte-Doolittle Hydrophobicity Value	-0.522
Molecular Weight (kDa)	62.3
Isoelectric Point (pI)	6.64

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
6EYS	OXIDOREDUCTASE	11/13/17	Crystal structure of the periplasmic pyoverdine maturation protein PvdP	Pseudomonas aeruginosa UCBPP-PA14	2.091	X-RAY DIFFRACTION	100.0
6RRR	OXIDOREDUCTASE	05/20/19	Crystal structure of the tyrosinase PvdP from Pseudomonas aeruginosa	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	2.11	X-RAY DIFFRACTION	100.0
6RRQ	OXIDOREDUCTASE	05/20/19	Crystal structure of tyrosinase PvdP from Pseudomonas aeruginosa bound to copper	Pseudomonas aeruginosa PAO1	2.7	X-RAY DIFFRACTION	100.0
6EYV	OXIDOREDUCTASE	11/13/17	Crystal structure of the pyoverdine maturation protein PvdP in complex with the mock substrates L-tyrosine and zinc.	Pseudomonas aeruginosa (strain UCBPP-PA14)	2.704	X-RAY DIFFRACTION	100.0
6RRP	OXIDOREDUCTASE	05/20/19	Crystal structure of tyrosinase PvdP from Pseudomonas aeruginosa bound to copper and phenylthiourea	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	2.4	X-RAY DIFFRACTION	100.0

Virulence Evidence

Source 1
Database	VFDB
Category	Pyoverdine
Evidence
Host Organism
Notes
Reference

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 6 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003135 (466 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA2392 Search term: pvdP Search term: PvdP

Human Homologs

References

GeneChip expression analysis of the iron starvation response in Pseudomonas aeruginosa: identification of novel pyoverdine biosynthesis genes. Ochsner UA, Wilderman PJ, Vasil AI, Vasil ML Mol Microbiol 2002 Sep;45(5):1277-87 PubMed ID: 12207696

Identification and characterization of novel pyoverdine synthesis genes in Pseudomonas aeruginosa. Lamont IL, Martin LW Microbiology (Reading) 2003 Apr;149(Pt 4):833-842 PubMed ID: 12686626