Pseudomonas aeruginosa PAO1, PA1999 (dhcA)

Annotation Updates

Date	Description	Acknowledgements
May 15, 2009	New gene name: dhcA. New product name: DhcA, dehydrocarnitine CoA transferase, subunit A. New product name confidence: Class 1. New comment: Deletion of dhcA or transposon insertions into the coding sequence result in a strain unable to grow using L-carnitine as a sole carbon source. DhcA is predicted to form a complex with DhcB which functions to deacetylate 3-dehydrocarnitine generating acetyl-CoA and glycine betaine CoA. Deletion of the dhcAB operon results in complete loss of carnitine-dependent CoA utilization from cytoplasmic extracts compared to cytoplasm from wild-type cells.; Transcription of the dhcAB operon is regulated by the transcription factor DhcR. . New evidence reference (PMID): 19406895. New genomic context: dhcAB operon.	Matthew J. Wargo (University of Vermont College of Medicine) and Deborah A. Hogan (Dartmouth Medical School)
Jul 29, 2010	New subcellular localization: Cytoplasmic. New subcellular localization confidence: Class 1. New evidence reference (PMID): 20472543.	Nancy Yu, Brinkman Lab, Simon Fraser University, Canada
Mar 12, 2019	Fixed typo in gene and product names. Reverted back to the correct name provided in PMID: 19406895.	Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada