Pseudomonas aeruginosa PAO1, PA1756 (cysH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0009973 adenylyl-sulfate reductase activity
IGI
Inferred from Genetic Interaction 		ECO:0000316
genetic interaction evidence used in manual assertion		 10613872 Reviewed by curator
Biological Process GO:0000103 sulfate assimilation
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 10613872 Reviewed by curator
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01507
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004604 phosphoadenylyl-sulfate reductase (thioredoxin) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000857
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019344 cysteine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02055
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019379 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000857
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-781 sulfate assimilation 2 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00920 Sulfur metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF01507 Phosphoadenosine phosphosulfate reductase family IPR002500 Phosphoadenosine phosphosulphate reductase 57 234 1.7E-47
NCBIfam TIGR02055 JCVI: adenylylsulfate reductase, thioredoxin dependent IPR011798 Adenosine 5'-phosphosulphate reductase 63 258 4.6E-86
SUPERFAMILY SSF52402 Adenine nucleotide alpha hydrolases-like - - 32 222 1.87E-46
MobiDBLite mobidb-lite consensus disorder prediction - - 10 24 -
FunFam G3DSA:3.40.50.620:FF:000153 Phosphoadenosine phosphosulfate reductase - - 28 249 0.0
PIRSF PIRSF000857 PAPS_reductase IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase 10 264 4.7E-81
Hamap MF_00063 Adenosine 5'-phosphosulfate reductase [cysH]. IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase 23 260 35.598804
NCBIfam TIGR00434 JCVI: phosophoadenylyl-sulfate reductase IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase 42 259 4.6E-50
MobiDBLite mobidb-lite consensus disorder prediction - - 1 25 -
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 28 249 5.6E-75
PANTHER PTHR46482 5'-ADENYLYLSULFATE REDUCTASE 3, CHLOROPLASTIC - - 13 265 1.5E-100
CDD cd01713 PAPS_reductase IPR002500 Phosphoadenosine phosphosulphate reductase 59 227 2.3172E-54

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.