Pseudomonas aeruginosa PAO1, PA1614 (gpsA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0046474 glycerophospholipid biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 4591941 Reviewed by curator
Molecular Function GO:0047952 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 355254 Reviewed by curator
Cellular Component GO:0009331 glycerol-3-phosphate dehydrogenase complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000114
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01210
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0047952 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000114
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01210
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.1040.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006072 glycerol-3-phosphate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000114
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0046168 glycerol-3-phosphate catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01210
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0005975 carbohydrate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07479
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Fatty acid and phospholipid metabolism Other PAO1 genes in this class
Central intermediary metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCyc AERO-GLYCEROL-FERM-PWY aerobic glycerol degradation I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
MetaCyc CDP-diacylglycerol biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc CDP-diacylglycerol biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PHOSLIPSYN-PWY superpathway of phospholipid biosynthesis I (bacteria) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCAP Glycerolipid metabolism ECO:0000037
not_recorded
PseudoCyc PWY0-1319 CDP-diacylglycerol biosynthesis II 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00564 Glycerophospholipid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-5667 CDP-diacylglycerol biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
MetaCyc glucosylglycerol biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:1.10.1040.10 - IPR013328 6-phosphogluconate dehydrogenase, domain 2 189 334 3.4E-47
PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent 238 255 2.0E-38
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 7 178 2.68E-49
PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent 9 26 2.0E-38
PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent 173 197 2.0E-38
SUPERFAMILY SSF48179 6-phosphogluconate dehydrogenase C-terminal domain-like IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily 180 331 1.55E-49
PIRSF PIRSF000114 Glycerol-3-P_dh IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent 1 332 1.1E-107
FunFam G3DSA:3.40.50.720:FF:000019 Glycerol-3-phosphate dehydrogenase [NAD(P)+] - - 1 187 4.9E-63
PANTHER PTHR11728 GLYCEROL-3-PHOSPHATE DEHYDROGENASE - - 3 325 7.3E-78
Gene3D G3DSA:3.40.50.720 - - - 1 187 1.2E-60
Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal 180 320 7.9E-48
Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent 5 322 35.395977
FunFam G3DSA:1.10.1040.10:FF:000001 Glycerol-3-phosphate dehydrogenase [NAD(P)+] - - 189 333 3.9E-53
PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent 59 86 2.0E-38
PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent 133 153 2.0E-38
PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent 198 222 2.0E-38
Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal 7 160 1.9E-51

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.