Pseudomonas aeruginosa PAO1, PA1598

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF51621
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0015940 pantothenate biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000388
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003864 3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000388
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Putative enzymes Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00770 Pantothenate and CoA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF02548 Ketopantoate hydroxymethyltransferase IPR003700 Ketopantoate hydroxymethyltransferase 10 264 1.6E-99
PIRSF PIRSF000388 PanB IPR003700 Ketopantoate hydroxymethyltransferase 1 272 1.9E-99
CDD cd06557 KPHMT-like IPR003700 Ketopantoate hydroxymethyltransferase 12 263 0.0
Coils Coil Coil - - 239 259 -
Gene3D G3DSA:3.20.20.60 - IPR040442 Pyruvate kinase-like domain superfamily 1 269 3.5E-97
FunFam G3DSA:3.20.20.60:FF:000003 3-methyl-2-oxobutanoate hydroxymethyltransferase - - 7 271 2.2E-92
Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. IPR003700 Ketopantoate hydroxymethyltransferase 10 269 40.550411
NCBIfam TIGR00222 JCVI: 3-methyl-2-oxobutanoate hydroxymethyltransferase IPR003700 Ketopantoate hydroxymethyltransferase 15 269 3.4E-92
PANTHER PTHR20881 3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE IPR003700 Ketopantoate hydroxymethyltransferase 5 272 1.1E-90
SUPERFAMILY SSF51621 Phosphoenolpyruvate/pyruvate domain IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily 10 269 3.51E-94

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.