Pseudomonas aeruginosa PAO1, PA1373 (fabF2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 9013860 Reviewed by curator
Molecular Function GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR03150
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006633 fatty acid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR03150
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016746 transferase activity, transferring acyl groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.47.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Fatty acid and phospholipid metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00061 Fatty acid biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc FASYN-ELONG-PWY fatty acid elongation -- saturated 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00780 Biotin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01212 Fatty acid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00834 KAS_I_II IPR000794 Beta-ketoacyl synthase 3 418 0.0
PIRSF PIRSF000447 KAS_II IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 1 422 0.0
SUPERFAMILY SSF53901 Thiolase-like IPR016039 Thiolase-like 223 421 3.46E-64
PANTHER PTHR11712 POLYKETIDE SYNTHASE-RELATED IPR000794 Beta-ketoacyl synthase 2 420 0.0
NCBIfam TIGR03150 JCVI: beta-ketoacyl-ACP synthase II IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 3 419 0.0
Gene3D G3DSA:3.40.47.10 - IPR016039 Thiolase-like 1 421 2.3E-130
SUPERFAMILY SSF53901 Thiolase-like IPR016039 Thiolase-like 3 261 1.52E-73
Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain IPR014031 Beta-ketoacyl synthase, C-terminal 265 378 9.4E-33
Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain IPR014030 Beta-ketoacyl synthase, N-terminal 3 256 1.5E-59
FunFam G3DSA:3.40.47.10:FF:000009 3-oxoacyl-[acyl-carrier-protein] synthase 2 - - 1 421 0.0
SMART SM00825 Beta-ketoacyl synthase IPR020841 Polyketide synthase, beta-ketoacyl synthase domain 5 421 5.0E-13

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.