Pseudomonas aeruginosa PAO1, PA0949 (wrbA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0034599 cellular response to oxidative stress
IMP
Inferred from Mutant Phenotype 		ECO:0000315
mutant phenotype evidence used in manual assertion		 25085734 Reviewed by curator
Molecular Function GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 16672604 Reviewed by curator
Molecular Function GO:0003674 molecular_function

Biological Process GO:0016070 RNA metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0003955 NAD(P)H dehydrogenase (quinone) activity
IMP
Inferred from Mutant Phenotype 		ECO:0000315
mutant phenotype evidence used in manual assertion		 25085734 Reviewed by curator
Molecular Function GO:0010181 FMN binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01755
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03358
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003955 NAD(P)H dehydrogenase (quinone) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01755
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcription, RNA processing and degradation Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc superpathway of photosynthetic hydrogen production InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc vitamin K-epoxide cycle InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae00130 Ubiquinone and other terpenoid-quinone biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.50.360 - IPR029039 Flavoprotein-like superfamily 1 198 1.3E-68
PANTHER PTHR30546 FLAVODOXIN-RELATED PROTEIN WRBA-RELATED - - 6 196 3.5E-42
Coils Coil Coil - - 198 198 -
Pfam PF03358 NADPH-dependent FMN reductase IPR005025 NADPH-dependent FMN reductase-like 13 141 2.4E-9
NCBIfam TIGR01755 JCVI: NAD(P)H:quinone oxidoreductase, type IV IPR010089 Flavoprotein WrbA-like 6 196 9.5E-45
SUPERFAMILY SSF52218 Flavoproteins IPR029039 Flavoprotein-like superfamily 4 196 2.49E-64
FunFam G3DSA:3.40.50.360:FF:000001 NAD(P)H dehydrogenase (Quinone) FQR1-like - - 1 198 1.7E-68

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.