Pseudomonas sp. MOIL14HWK12:I2, PSK12I2_RS0106345

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003911 DNA ligase (NAD+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00575
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00575
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00575
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00278
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF01653 NAD-dependent DNA ligase adenylation domain IPR013839 NAD-dependent DNA ligase, adenylation 7 331 3.2E-125
PANTHER PTHR23389 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 - - 7 772 9.8E-51
FunFam G3DSA:2.40.50.140:FF:000012 DNA ligase - - 330 403 9.3E-35
CDD cd00114 LIGANc IPR013839 NAD-dependent DNA ligase, adenylation 9 330 0.0
FunFam G3DSA:1.10.150.20:FF:000007 DNA ligase - - 455 530 2.1E-29
SUPERFAMILY SSF52113 BRCT domain IPR036420 BRCT domain superfamily 715 790 2.24E-18
Gene3D G3DSA:1.10.150.20 - - - 530 610 1.4E-25
Gene3D G3DSA:1.10.150.20 - - - 455 529 2.4E-27
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 331 413 5.48E-28
Gene3D G3DSA:3.30.470.30 DNA ligase/mRNA capping enzyme - - 69 328 6.3E-98
Gene3D G3DSA:3.40.50.10190 BRCT domain IPR036420 BRCT domain superfamily 704 790 1.4E-25
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 537 556 57.0
FunFam G3DSA:1.10.287.610:FF:000002 DNA ligase - - 2 67 1.2E-27
Gene3D G3DSA:6.20.10.30 - - - 404 454 1.2E-13
NCBIfam TIGR00575 JCVI: DNA ligase (NAD(+)) LigA IPR001679 NAD-dependent DNA ligase 14 615 0.0
SMART SM00532 ligaN3 IPR013840 NAD-dependent DNA ligase, N-terminal 6 473 0.0
FunFam G3DSA:3.30.470.30:FF:000001 DNA ligase - - 68 328 1.8E-105
SUPERFAMILY SSF56091 DNA ligase/mRNA capping enzyme, catalytic domain - - 4 329 2.34E-116
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 417 608 7.41E-53
SMART SM00292 BRCT_7 IPR001357 BRCT domain 714 791 5.2E-12
FunFam G3DSA:1.10.150.20:FF:000006 DNA ligase - - 531 608 2.0E-23
CDD cd17748 BRCT_DNA_ligase_like - - 717 787 6.76307E-27
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 624 706 3.34E-5
Pfam PF00533 BRCA1 C Terminus (BRCT) domain IPR001357 BRCT domain 714 787 4.3E-12
Hamap MF_01588 DNA ligase [ligA]. IPR001679 NAD-dependent DNA ligase 5 788 52.871017
Pfam PF03120 NAD-dependent DNA ligase OB-fold domain IPR004150 NAD-dependent DNA ligase, OB-fold 335 411 7.2E-35
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 330 403 1.3E-32
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 1 625 0.0
Gene3D G3DSA:1.10.150.20 - - - 623 703 2.1E-5
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 505 524 450.0
Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type 420 459 1.3E-12
Gene3D G3DSA:1.10.287.610 Helix hairpin bin - - 1 68 1.2E-26
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 617 793 7.4E-30
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 471 490 130.0
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 569 588 690.0
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 535 598 1.2E-19

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.