Log of Annotation Updates

60 annotation updates returned
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Date Locus Tag Strain Description Submitter
Jan 24, 2007 PA0836.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA0836.1. Start: 912791. Stop: 912861. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA0887.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA0887.1. Start: 971858. Stop: 971972. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA1030.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA1030.1. Start: 1117532. Stop: 1117609. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA1324.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA1324.1. Start: 1436491. Stop: 1436618. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA1781.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA1781.1. Start: 1928886. Stop: 1928666. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA2942.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA2942.1. Start: 3299022. Stop: 3299269. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA2958.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA2958.1. Start: 3318663. Stop: 3318859. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA3304.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA3304.1. Start: 3703156. Stop: 3703022. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA3305.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA3305.1. Start: 3705622. Stop: 3705315. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA4270.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA4270.1. Start: 4780833. Stop: 4780768. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA4272.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA4272.1. Start: 4781786. Stop: 4781978. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA4421.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA4421.1. New gene name: rnpB. Start: 4956328. Stop: 4956536. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene.. New product name: "RNA component of RNaseP, RnpB". Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA4451.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA4451.1. Start: 4985843. Stop: 4985782. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA4726.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA4726.1. Start: 5308433. Stop: 5308493. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA4726.2 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA4726.2. Start: 5308964. Stop: 5308743. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA4758.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA4758.1. Start: 5345060. Stop: 5344950. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA5181.1 Pseudomonas aeruginosa PAO1 New gene (sRNA). New locusID: PA5181.1. Start: 5835480. Stop: 5835082. New evidence reference (PubMed ID): 16870723. New PseudoCAP function class: Non-coding RNA gene. New evidence reference (PubMedID): 16477007 Jonathan Livny, Department of Molecular Biology and Microbiology, Tufts University School of Medicine and Howard Hughes Medical Institute.
Jan 24, 2007 PA0169 Pseudomonas aeruginosa PAO1 New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases . Deleting structue feature: PF00990: Domain of unknown function. New evidence reference (PubMedID): 16477007 Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA0285 Pseudomonas aeruginosa PAO1 Deleting structue feature: PF00990: Domain of unknown function. Deleting structue feature: PF00563: Domain of unknown function 2. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. New evidence reference (PubMedID): 16477007 Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA0290 Pseudomonas aeruginosa PAO1 Deleting structue feature: PF00990: Domain of unknown function. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. New evidence reference (PMID): 16477007. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA0338 Pseudomonas aeruginosa PAO1 New evidence reference (PMID): 16477007. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases . Deleting structue feature: PF00990: Domain of unknown function. New comment: Overexpression of PA0338 increaes pellicle formation. New PseudoCAP function class: Motility & Attachment. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA0575 Pseudomonas aeruginosa PAO1 Deleting structue feature: PF00990: Domain of unknown function. Deleting structue feature: PF00563: Domain of unknown function 2. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. New evidence reference (PMID): 16477007. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA0847 Pseudomonas aeruginosa PAO1 New evidence reference (PMID): 16477007. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases . Deleting structue feature: PF00990: Domain of unknown function weak and only partial). New comment: Overexpression of PA0847 increaes pellicle formation. . Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Nucleotide biosynthesis and metabolism. New PseudoCAP function class: Motility & Attachment. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA0861 Pseudomonas aeruginosa PAO1 New PseudoCAP function class: Motility & Attachment. New evidence reference (PMID): 16477007. Deleting function class: Hypothetical, unclassified, unknown. Deleting structue feature: PF00563: Domain of unknown function 2. Deleting structue feature: PF00990: Domain of unknown function. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA1107 Pseudomonas aeruginosa PAO1 New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. Deleting structue feature: PF00990: Domain of unknown function. New evidence reference (PMID): 16477007. New comment: Overexpression of PA1107 increases pellicle formation. . Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Nucleotide biosynthesis and metabolism. New PseudoCAP function class: Motility & Attachment. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA1120 Pseudomonas aeruginosa PAO1 New PseudoCAP function class: Motility & Attachment. New PseudoCAP function class: Nucleotide biosynthesis and metabolism. Deleting function class: Hypothetical, unclassified, unknown. New evidence reference (PMID): 16477007. New comment: Overexpression of PA1120 increases pellicle formation. . New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA1181 Pseudomonas aeruginosa PAO1 Deleting structue feature: PF00990: Domain of unknown function. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. New evidence reference (PMID): 16477007. Deleting function class: Hypothetical, unclassified, unknown. Deleting structue feature: PF00563: Domain of unknown function 2. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA1433 Pseudomonas aeruginosa PAO1 New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. Deleting structue feature: PF00990: Domain of unknown function (weak and partial). Deleting structue feature: PF00563: Domain of unknown function 2. New evidence reference (PMID): 16477007. Deleting function class: Hypothetical, unclassified, unknown. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA1727 Pseudomonas aeruginosa PAO1 Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Nucleotide biosynthesis and metabolism. New PseudoCAP function class: Motility & Attachment. New evidence reference (PMID): 16477007. Deleting structue feature: PF00563: Domain of unknown function 2. Deleting structue feature: PF00990: Domain of unknown function. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). New comment: Overexpression of PA1727 increases pellicle formation. . Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA1851 Pseudomonas aeruginosa PAO1 Deleting structue feature: PF00990: Domain of unknown function. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. New evidence reference (PMID): 16477007. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA2072 Pseudomonas aeruginosa PAO1 New evidence reference (PMID): 16477007. Deleting structue feature: PF00990: Domain of unknown function. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA2133 Pseudomonas aeruginosa PAO1 New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). New evidence reference (PMID): 16477007. New comment: Overexpression of PA2133 results in impaired TTSS-mediated cytotoxicity. Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Nucleotide biosynthesis and metabolism. Deleting structue feature: PF00563: Domain of unknown function 2. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA2200 Pseudomonas aeruginosa PAO1 Deleting structue feature: PF00563: Domain of unknown function 2. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Nucleotide biosynthesis and metabolism. New evidence reference (PMID): 16477007. New comment: Overexpression of PA2200 results in impaired TTSS-mediated cytotoxicity. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA2567 Pseudomonas aeruginosa PAO1 Deleting structue feature: PF00563: Domain of unknown function 2. New evidence reference (PMID): 16477007. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA2771 Pseudomonas aeruginosa PAO1 New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. Deleting structue feature: PF00990: Domain of unknown function. New evidence reference (PMID): 16477007. New comment: GGDEF motifs found in PAO1 and PACS2, but not PA14. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA2818 Pseudomonas aeruginosa PAO1 Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Nucleotide biosynthesis and metabolism. New comment: EAL motifs found in PAO1 and PACS2, but not PA14. New comment: Overexpression of PA2818 increaes pellicle formation. Deleting structue feature: PF00563: Domain of unknown function 2. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). New evidence reference (PMID): 16477007. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA2870 Pseudomonas aeruginosa PAO1 New evidence reference (PMID): 16477007. Deleting structue feature: PF00990: Domain of unknown function. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. New structure feature: Overexpression of PA2870 increases pellicle formation . Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Nucleotide biosynthesis and metabolism. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA3177 Pseudomonas aeruginosa PAO1 Deleting structue feature: PF00990: Domain of unknown function. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. New evidence reference (PMID): 16477007. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA3258 Pseudomonas aeruginosa PAO1 New evidence reference (PMID): 16477007. Deleting structue feature: PF00563: Domain of unknown function 2. Deleting structue feature: PF00990: Domain of unknown function (weak). New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA3311 Pseudomonas aeruginosa PAO1 Deleting structue feature: PF00563: Domain of unknown function 2. Deleting structue feature: PF00990: Domain of unknown function. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. New evidence reference (PMID): 16477007. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA3343 Pseudomonas aeruginosa PAO1 Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Nucleotide biosynthesis and metabolism. New PseudoCAP function class: Motility & Attachment. New evidence reference (PMID): 16477007. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. Deleting structue feature: PF00990: Domain of unknown function. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA3702 Pseudomonas aeruginosa PAO1 Deleting structue feature: PF00990: Domain of unknown function. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. New evidence reference (PMID): 16477007. New comment: Overexpression of PA3702 causes increased pellicle formation. . New PseudoCAP function class: Nucleotide biosynthesis and metabolism. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA3825 Pseudomonas aeruginosa PAO1 New PseudoCAP function class: Nucleotide biosynthesis and metabolism. Deleting function class: Hypothetical, unclassified, unknown. New evidence reference (PMID): 16477007. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). Deleting structue feature: PF00563: Domain of unknown function 2. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA3947 Pseudomonas aeruginosa PAO1 New gene name: rocR (Existing value: blank). New product name: RocR (Existing value: probable two-component response regulator). New evidence reference (PMID): 15659157. New product name confidence: Class 1 (Existing value: Class 3). Deleting structue feature: PF00563: Domain of unknown function 2. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). New comment: Overexpression of PA3947 impairs TTSS-mediated cytotoxicity. New evidence reference (PMID): 16477007. New PseudoCAP function class: Nucleotide biosynthesis and metabolism. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA4332 Pseudomonas aeruginosa PAO1 Deleting structue feature: PF00990: Domain of unknown function. New evidence reference (PMID): 16477007. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Motility & Attachment. New comment: Overexpression of PA4332 causes increased pellicle formation . Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA4367 Pseudomonas aeruginosa PAO1 Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Motility & Attachment . New evidence reference (PMID): 16477007. Deleting structue feature: PF00563: Domain of unknown function 2. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). Deleting structue feature: PF00990: Domain of unknown function. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. New comment: Overexpression of PA4367 impairs TTSS-mediated cytotoxicity. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA4396 Pseudomonas aeruginosa PAO1 New comment: Overexpression of PA4396 impairs TTSS-mediated cytotoxicity. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases . New evidence reference (PMID): 16477007. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA4601 Pseudomonas aeruginosa PAO1 New evidence reference (PMID): 16477007. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. Deleting structue feature: PF00990: Domain of unknown function. Deleting structue feature: PF00563: Domain of unknown function 2. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA4843 Pseudomonas aeruginosa PAO1 New evidence reference (PMID): 16477007. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. Deleting structue feature: PF00990: Domain of unknown function. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA4929 Pseudomonas aeruginosa PAO1 Deleting structue feature: PF00990: Domain of unknown function. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. New evidence reference (PMID): 16477007. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA4959 Pseudomonas aeruginosa PAO1 New evidence reference (PMID): 16477007. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA5017 Pseudomonas aeruginosa PAO1 New evidence reference (PMID): 16477007. Deleting structue feature: PF00563: Domain of unknown function 2. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). Deleting structue feature: PF00990: Domain of unknown function. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Motility & Attachment. New comment: Overexpression of PA5017 impairs TTSS-mediated cytotoxicity. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA5295 Pseudomonas aeruginosa PAO1 New evidence reference (PMID): 16477007. Deleting structue feature: PF00563: Domain of unknown function 2. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). Deleting structue feature: PF00990: Domain of unknown function. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA5442 Pseudomonas aeruginosa PAO1 New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. Deleting structue feature: PF00990: Domain of unknown function. Deleting structue feature: PF00563: Domain of unknown function 2. New structure feature: PF00563: Domain of unknown function 2. New evidence reference (PMID): 16477007. New comment: Overexpression of PA5442 impairs TTSS-mediated cytotoxicity. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA5487 Pseudomonas aeruginosa PAO1 New evidence reference (PMID): 16477007. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. Deleting structue feature: PF00990: Domain of unknown function. Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Nucleotide biosynthesis and metabolism. New comment: Overexpression PA5487 increases pellicle formation. Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA3946 Pseudomonas aeruginosa PAO1 New evidence reference (PMID): 15659157. New gene name: rocS1. (Existing value: blank). New product name: two-component sensor RocS1. (Existing value: blank). New product name confidence: Class 1 (Existing value: Class 3). Literature review. Approved by reference author Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA3948 Pseudomonas aeruginosa PAO1 New product name confidence: Class 1 (Existing value: Class 3). New product name: two-component response regulator RocA1 (Existing value: probable two-component response regulator). New gene name: rocA1 (Existing value: blank). New evidence reference (PMID): 15659157. Literature review. Approved by reference author Hemantha Kulasekara, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA.
Jan 24, 2007 PA0423 Pseudomonas aeruginosa PAO1 New gene name: pasP (Existing value: blank). New product name: PasP (Existing value: conserved hypothetical protein). New product name confidence: Class 1 (Existing value: Class 4). New PseudoCAP function class: Secreted Factors (toxins, enzymes, alginate). New subcellular localization: Extracellular (Existing value: Unknown). New subcellular localization confidence: Class 1 (Existing value: Class 3). New evidence reference (PMID): 16186360. Literature review. Approved by reference author Richard O'Callaghan, University of Mississippi Medical Center, USA.
Jan 24, 2007 PA3713 Pseudomonas aeruginosa PAO1 New subcellular localization: Inner membrane (Existing value: Unknown). New subcellular localization confidence: Class 1 (Existing value: Class 3). New EC number: 1.5.99.6. New evidence reference (PMID): 16849793. New product name confidence: Class 1 (Existing value: Class 4). New product name: spermidine dehydrogenase, SpdH (Existing value: hypothetical protein). New gene name: spdH (Existing value: blank). New homology: 43% similar and 56% identical to SpdH [Chromobacterium violaceum],and [ Campylobacter lari]. New structure feature: signal sequence of 28 amino acids and a potential transmembrane segment. New comment: Cleaved spermidine into 1, 3-diaminopropane and 4-aminobutyraldehyde. Hydrolyzed spermine into spermidine and 3-aminopropanaldehyde. Literature review. Approved by reference author Yoshifumi Itoh, Tohoku University, Japan.
Jan 24, 2007 PA4175 Pseudomonas aeruginosa PAO1 New gene name: piv (Existing value: prpL). New alternate gene name: prpL . New product name: protease IV (Existing value: Pvds-regulated endoprotease, lysyl class). New alternate product name: Pvds-regulated endoprotease, lysyl class. New PseudoCAP function class: Secreted Factors (toxins, enzymes, alginate). New comment: protease IV is an ocular virulence factor (rabbit model).. New evidence reference (PMID): 8595953. New evidence reference (PMID): 9224281. New evidence reference (PMID): 9501882. New evidence reference (PMID): 9642237. New evidence reference (PMID): 11237336. New evidence reference (PMID): 12419815. New evidence reference (PMID): 14744894. New evidence reference (PMID): 12506074. New evidence reference (PMID): 14628143. New evidence reference (PMID): 16019676. New evidence reference (PMID): 15516485. Richard O'Callaghan, Dept. of Microbiology, University of Mississippi Medical Center, USA.
60 annotation updates returned