| Sep 5, 2006 |
PA0836
|
Pseudomonas aeruginosa
PAO1 |
New gene name: ackA (Existing value: blank). Deleting alternate gene name: ackA. New product name: acetate kinase (Existing value: probable acetate kinase). New product name confidence: Class 2 (Existing value: Class 3). New EC number: 2.7.2.1. Deleted EC number: 2.7.2.-. New pathway: Pyruvate metabolism. New evidence reference (PMID): 15231792.
|
Literature review. Approved by reference author Max Schobert, Institut fuer Mikrobiologie, Germany.
|
| Sep 5, 2006 |
PA0835
|
Pseudomonas aeruginosa
PAO1 |
New evidence reference (PMID): 15231792. New product name confidence: Class 1 (Existing value: Class 2).
|
Max Schobert, Institut fuer Mikrobiologie, Germany.
|
| Sep 5, 2006 |
PA3309
|
Pseudomonas aeruginosa
PAO1 |
New alternate gene name: uspK. New alternate product name: UspK, Usp-type stress protein essential for survival during pyruvate fermentation. New product name confidence: Class 1 (Existing value: Class 4). New evidence reference (PMID): 16385055.
|
Max Schobert, Institut fuer Mikrobiologie, Germany.
|
| Sep 5, 2006 |
PA1003
|
Pseudomonas aeruginosa
PAO1 |
New product name: Transcriptional regulator MvfR. (Existing value: Transcriptional regulator). New subcellular localization: Cytoplasmic Membrane (Existing value: Unknown). New subcellular localization confidence: Class 1 (Existing value: Class 3). New genomic context: MvfR controls the pqsABCDE and phnAB operons, which encode proteins mediating 4-hydroxy-2-alkylquinoline biosynthesis. New genomic context: MvfR dimer activates pqsA-E transcription by binding to a LysR box, TTCGGACTCCGAA, centred at -45 bp relative to the pqsA transcriptional initiation site. New evidence reference (PMID): 16735731. New evidence reference (PMID): 14739337. New evidence reference (PMID): 11724939. New evidence reference (PMID): 15686549.
|
Literature review. Approved by reference author Laurence G. Rahme, Harvard University, USA.
|
| Sep 5, 2006 |
PA3477
|
Pseudomonas aeruginosa
PAO1 |
New evidence reference (PMID): 16735731. New subcellular localization: Cytoplasmic (Existing value: Unknown). New subcellular localization confidence: Class 1 (Existing value: Class 3). New genomic context: RhlR protein binds to the -311 las/rhl box, CTGTGAGATTTGGGAG in the pqsA promoter to repress pqsA-E transcription.
|
Laurence G. Rahme, Harvard University, USA.
|
| Sep 5, 2006 |
PA4944
|
Pseudomonas aeruginosa
PAO1 |
New gene name: hfq (Existing value: blank). Deleting alternate gene name: hfq. New product name: Hfq (Existing value: conserved hypothetical protein). New product name confidence: Class 1 (Existing value: Class 4). New PseudoCAP function class: Transcription, RNA processing and degradation. New subcellular localization: Cytoplasmic (Existing value: Unknown). New subcellular localization confidence: Class 1 (Existing value: Class 3). New evidence reference (PMID): 16468994. New evidence reference (PMID): 14521880.
|
Literature Review. Approved by reference authors Elisabeth Sonnleitner and Udo Blasi, University of Vienna, Austria.
|
| Sep 5, 2006 |
PA3351
|
Pseudomonas aeruginosa
PAO1 |
New gene name: flgM (Existing value: blank). Deleted alternate gene name: flgM. New product name: FlgM. New product name confidence: Class 1 (Existing value: Class 4). New PseudoCAP function class: Transcriptional regulators. New comment: FlgM protein physically interacts with the alternative sigma factor FliA (PA1455). New homology: 61% similarity and 31% identity to FlgM [Vibrio parahaemolyticus] . New homology: 61% similarity and 28% identity to FlgM [Vibrio cholerae]. New homology: 57% similarity and 38% identity to FlgM [Proteus mirabilis] . New evidence reference (PMID): 11872701.
|
Literature Review. Approved by reference author Reuben Ramphal, University of Florida, USA.
|
| Sep 5, 2006 |
PA0286
|
Pseudomonas aeruginosa
PAO1 |
New gene name: desA (Existing value: blank). New product name: delta-9 fatty acid desaturase, DesA (Existing value: probable fatty acid desaturase). New product name confidence: Class 1 (Existing value: Class 3). New evidence reference (PMID): 16573679. New PseudoCAP function class: Fatty acid and phospholipid metabolism.
|
Literature Review. Approved by reference author Yong-Mei Zhang, St. Jude Children's Research Hospital, USA.
|
| Sep 5, 2006 |
PA4888
|
Pseudomonas aeruginosa
PAO1 |
New PseudoCAP function class: Fatty acid and phospholipid metabolism. New gene name: desB (Existing value: blank). New product name: acyl-CoA delta-9-desaturase, DesB (Existing value: conserved hypothetical protein). New product name confidence: Class 1 (Existing value: Class 4). New homology: 47% identical to acyl-CoA desaturase DesA [Mycobacterium tuberculosis]. New evidence reference (PMID): 16573679.
|
Literature Review. Approved by reference author Yong-Mei Zhang, St. Jude Children's Research Hospital, USA.
|
| Sep 5, 2006 |
PA4890
|
Pseudomonas aeruginosa
PAO1 |
New evidence reference (PMID): 16573679. New gene name: desT (Existing value: blank). New product name: DesT (Existing value: conserved hypothetical protein). New product name confidence: Class 1 (Existing value: Class 4). New PseudoCAP function class: Transcriptional regulators. Deleting function class: Hypothetical, unclassified, unknown. New comment: DesT negatively regulates both desB (PA4888) and PA4889.
|
Literature Review. Approved by reference author Yong-Mei Zhang, St. Jude Children's Research Hospital, USA.
|
| Sep 5, 2006 |
PA0005
|
Pseudomonas aeruginosa
PAO1 |
New EC number: 2.3.1.51. New pathway: phospholipid biosynthesis. Mapped from BRENDA Comprehensive Enzyme Information System (http://www.brenda.uni-koeln.de/php/result_flat.php4?ecno=2.3.1.51&organism=) and MetaCyc (http://biocyc.org/META/NEW-IMAGE? type=REACTION&object=1-ACYLGLYCEROL-3-P-ACYLTRANSFER-RXN).
|
Geoffrey L. Winsor and Fiona S.L. Brinkman. Simon Fraser University, Canada.
|