Pseudomonas Project PRJNA490053

Project Title Sub-inhibitory concentrations of kanamycin fix fusA mutation in an environmental Pseudomonas sp.
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Project Database BioProject
Project Accession PRJNA490053
Organism Name Pseudomonas protegens
Project Description Antibiotics can disseminate into the environment and persist at sub-inhibitory concentrations. It is not known what effect such low levels of pollution might have on environmental organisms. Here we have shown that environmental levels of antibiotics can rapidly fix a mutation in an environmental bacterium which correlates with a four-fold increase in antibiotic resistance. This shows that selection can be driven by low concentrations of antibiotics and suggests that similar selection events could be occurring at a high frequency in all environmental bacteria, disrupting normal microbial processes and contributing to the global problem of antibiotic resistance.
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Biosamples associated with this project

Link 2 BioSample(s)