Pseudomonas aeruginosa 19BR, IAI_RS0124965
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa 19BR
GCF_000223945.1|latest |
| Locus Tag |
IAI_RS0124965
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 5313388 - 5313981 (+ strand) |
Cross-References
| RefSeq | WP_003094149.1 |
| GI | 489184720 |
| NCBI Locus Tag | IAI_RS0124965 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
DnaA initiator-associating protein DiaA
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -7.89 |
| Kyte-Doolittle Hydrophobicity Value | -0.023 |
| Molecular Weight (kDa) | 21.4 |
| Isoelectric Point (pI) | 4.72 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 3BJZ | ISOMERASE | 12/05/07 | Crystal structure of Pseudomonas aeruginosa phosphoheptose isomerase | Pseudomonas aeruginosa PAO1 | 2.4 | X-RAY DIFFRACTION | 100.0 |
| 1X92 | ISOMERASE | 08/19/04 | CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA PHOSPHOHEPTOSE ISOMERASE IN COMPLEX WITH REACTION PRODUCT D-GLYCERO-D-MANNOPYRANOSE-7-PHOSPHATE | Pseudomonas aeruginosa | 2.3 | X-RAY DIFFRACTION | 100.0 |
Drugs Targeting this Protein
Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.
| Drug Name | Source Accession | Source DB | Version | Target Accession | Target Description | Percent Identity | Alignment Length | E-Value |
| D-Glycero-D-Mannopyranose-7-Phosphate | DB02470 | DrugBank | 5.1.4 | Q9HVZ0 | Phosphoheptose isomerase | 100.0 | 197 | 8.7e-104 |
Pathogen Association Analysis
| Results | Analysis not done |
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG004015 (536 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: IAI_RS0124965
Search term: DnaA initiator-associating protein DiaA
|
Human Homologs
References
No references are associated with this feature.