Pseudomonas aeruginosa 19BR, IAI_RS0118335

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa 19BR
GCF_000223945.1|latest
Locus Tag
IAI_RS0118335
Name
Replicon chromosome
Genomic location 3897415 - 3900186 (- strand)

Cross-References

RefSeq WP_003158825.1
GI 489250753
NCBI Locus Tag IAI_RS0118335

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA gyrase subunit A
Synonyms
Evidence for Translation
Charge (pH 7) -39.06
Kyte-Doolittle Hydrophobicity Value -0.243
Molecular Weight (kDa) 101.1
Isoelectric Point (pI) 4.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
Pseudomonas aeruginosa gyrA conferring resistance to fluoroquinolones Point mutation of Pseudomonas aeruginosa gyrA resulted in the lowered affinity between fluoroquinolones and gyrA. Thus, conferring resistance. [PMID:22821356, PMID:8540700] ARO:3003684 protein variant model T83I, D87N Strict 1748.0 99.78 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002447 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: IAI_RS0118335

Human Homologs

References

No references are associated with this feature.