Pseudomonas aeruginosa 19BR, IAI_RS0113240

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa 19BR
GCF_000223945.1|latest
Locus Tag
IAI_RS0113240
Name
Replicon chromosome
Genomic location 2873343 - 2874761 (+ strand)

Cross-References

RefSeq WP_003113303.1
GI 489204227
NCBI Locus Tag IAI_RS0113240

Product

Feature Type CDS
Coding Frame 1
Product Name
RND transporter
Synonyms
Evidence for Translation
Charge (pH 7) -6.52
Kyte-Doolittle Hydrophobicity Value -0.291
Molecular Weight (kDa) 51.2
Isoelectric Point (pI) 5.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
OprN OprN is the outer membrane channel component of the MexEF-OprN multidrug efflux complex. [PMID:10515918] ARO:3000805 protein homolog model Perfect 877.5 100.0 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5AZO MEMBRANE PROTEIN 10/21/15 Crystal structure of a membrane protein from Pseudomonas aeruginosa Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) 2.7 X-RAY DIFFRACTION 100.0
5NSW MEMBRANE PROTEIN 04/27/17 Xenon for tunnelling analysis of the efflux pump component OprN. Pseudomonas aeruginosa PAO1 2.5 X-RAY DIFFRACTION 100.0
5AZP MEMBRANE PROTEIN 10/21/15 Crystal structure of a membrane protein from Pseudomonas aeruginosa Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) 1.69 X-RAY DIFFRACTION 100.0
5IUY TRANSPORT PROTEIN 03/18/16 Structural insights of the outer-membrane channel OprN Pseudomonas aeruginosa PAO1 2.29 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003062 (529 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: IAI_RS0113240
Search term: RND transporter

Human Homologs

References

No references are associated with this feature.