Pseudomonas aeruginosa PAK, Y880_RS21705 (lbcA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAK - Assembly GCF_000568855.2
GCF_000568855.2|latest |
| Locus Tag |
Y880_RS21705
|
| Name |
lbcA
|
| Replicon | chromosome |
| Genomic location | 4544096 - 4545868 (+ strand) |
| Comment | Binding partner of CtpA (PA5134), required for CtpA proteolytic activity |
Cross-References
| RefSeq | WP_078451437.1 |
| GI | 0 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
LbcA
|
| Evidence for Translation | |
| Charge (pH 7) | -19.61 |
| Kyte-Doolittle Hydrophobicity Value | -0.527 |
| Molecular Weight (kDa) | 66261.8 |
| Isoelectric Point (pI) | 4.83 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 7RQF | PROTEIN BINDING | 08/06/21 | Crystal Structure of LbcA (lipoprotein binding partner of CtpA) of Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 3.5 | X-RAY DIFFRACTION | 99.6 |
Pathogen Association Analysis
| Results | Analysis not done |
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group | |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: Y880_RS21705
Search term: lbcA
Search term: LbcA
|
Human Homologs
References
|
A Proteolytic Complex Targets Multiple Cell Wall Hydrolases in Pseudomonas aeruginosa.
Srivastava D, Seo J, Rimal B, Kim SJ, Zhen S, Darwin AJ
mBio 2018 Jul 17;9(4)
PubMed ID: 30018106
|