Pseudomonas putida KT2440, PP_3546 (hskA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas putida KT2440 (TIGR)
GCF_000007565.2|latest |
| Locus Tag |
PP_3546
|
| Name |
hskA
|
| Replicon | chromosome |
| Genomic location | 4019290 - 4021356 (+ strand) |
| Comment | HskA is a hybrid sensor kinase controlling the composition of the electron transport chain in response to redox signals |
Cross-References
| RefSeq | NP_745683.1 |
| GI | 26990258 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
hybrid sensor kinase, HskA
|
| Synonyms |
two-component system sensor histidine kinase/response regulator |
| Evidence for Translation | |
| Charge (pH 7) | |
| Kyte-Doolittle Hydrophobicity Value | -0.215 |
| Molecular Weight (kDa) | 76.4 |
| Isoelectric Point (pI) | 5.20 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results | Analysis not done |
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group | |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PP_3546
Search term: hskA
Search term: hybrid sensor kinase, HskA
|
Human Homologs
References
|
The Pseudomonas putida HskA hybrid sensor kinase controls the composition of the electron transport chain.
Sevilla E, Silva-Jiménez H, Duque E, Krell T, Rojo F
Environ Microbiol Rep 2013 Apr;5(2):291-300
PubMed ID: 23584971
|
|
The Pseudomonas putida HskA hybrid sensor kinase responds to redox signals and contributes to the adaptation of the electron transport chain composition in response to oxygen availability.
Sevilla E, Alvarez-Ortega C, Krell T, Rojo F
Environ Microbiol Rep 2013 Dec;5(6):825-34
PubMed ID: 24249291
|