Pseudomonas balearica DSM6083 (=SP1402), CL52_RS11325 (fadH)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas balearica DSM6083 (=SP1402)
GCF_000818015.1|latest |
| Locus Tag |
CL52_RS11325
|
| Name |
fadH
Synonym: CL52_11525 |
| Replicon | chromosome |
| Genomic location | 2511316 - 2513352 (- strand) |
Cross-References
| RefSeq | WP_043220678.1 |
| GI | 759499851 |
| EC Number | 1.3.1.34 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
2,4-dienoyl-CoA reductase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -3.66 |
| Kyte-Doolittle Hydrophobicity Value | -0.056 |
| Molecular Weight (kDa) | 73.1 |
| Isoelectric Point (pI) | 6.64 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Drugs Targeting this Protein
Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.
| Drug Name | Source Accession | Source DB | Version | Target Accession | Target Description | Percent Identity | Alignment Length | E-Value |
| Flavin adenine dinucleotide | DB03147 | DrugBank | 5.1.4 | P42593 | 2,4-dienoyl-CoA reductase [NADPH] | 63.1 | 675 | 8.8e-249 |
| 5-Mercaptoethanol-2-Decenoyl-Coenzyme A | DB03698 | DrugBank | 5.1.4 | P42593 | 2,4-dienoyl-CoA reductase [NADPH] | 63.1 | 675 | 8.8e-249 |
| 2'-Monophosphoadenosine 5'-Diphosphoribose | DB03461 | DrugBank | 5.1.4 | P42593 | 2,4-dienoyl-CoA reductase [NADPH] | 63.1 | 675 | 8.8e-249 |
| Flavin mononucleotide | DB03247 | DrugBank | 5.1.4 | P42593 | 2,4-dienoyl-CoA reductase [NADPH] | 63.1 | 675 | 8.8e-249 |
Pathogen Association Analysis
| Results | Analysis not done |
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG002500 (829 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: CL52_RS11325
Search term: fadH
Search term: 2,4-dienoyl-CoA reductase
|
Human Homologs
References
No references are associated with this feature.