Pseudomonas aeruginosa 2192, PA2G_03214

Gene Feature Overview

Strain	Pseudomonas aeruginosa 2192 GCF_000152545.1|latest
Locus Tag	PA2G_03214
Name
Replicon	chromosome
Genomic location	3582624 - 3583766 (+ strand)

Cross-References

RefSeq	ZP_04935786.1
GI	254242464
NCBI Locus Tag	PA2G_03214
UniProtKB Acc	A3LEM4
UniProtKB ID	A3LEM4_PSEAE

Product

Feature Type	CDS
Coding Frame	1
Product Name	acetoin utilization protein
Synonyms
Evidence for Translation
Charge (pH 7)	-4.57
Kyte-Doolittle Hydrophobicity Value	-0.113
Molecular Weight (kDa)	41.0
Isoelectric Point (pI)	6.45

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
5G0X	HYDROLASE	03/23/16	Pseudomonas aeruginosa HDAH bound to acetate.	PSEUDOMONAS AERUGINOSA	1.7	X-RAY DIFFRACTION	99.7
5G10	HYDROLASE	03/23/16	Pseudomonas aeruginosa HDAH bound to 9,9,9 trifluoro-8,8-dihydroy-N-phenylnonanamide	PSEUDOMONAS AERUGINOSA	1.71	X-RAY DIFFRACTION	99.7
5G0Y	HYDROLASE	03/23/16	Pseudomonas aeruginosa HDAH unliganded.	PSEUDOMONAS AERUGINOSA	2.29	X-RAY DIFFRACTION	99.7
5G12	HYDROLASE	03/23/16	Pseudomonas aeruginosa HDAH (Y313F) unliganded.	PSEUDOMONAS AERUGINOSA	2.02	X-RAY DIFFRACTION	99.5
5G13	HYDROLASE	03/23/16	Pseudomonas aeruginosa HDAH (H143A) unliganded.	PSEUDOMONAS AERUGINOSA	1.99	X-RAY DIFFRACTION	99.5
5LI3	SIGNALING PROTEIN	07/14/16	Crystal structure of HDAC-like protein from P. aeruginosa in complex with a photo-switchable inhibitor.	Pseudomonas aeruginosa	2.4	X-RAY DIFFRACTION	99.7
5G11	HYDROLASE	03/23/16	Pseudomonas aeruginosa HDAH bound to PFSAHA.	PSEUDOMONAS AERUGINOSA	2.48	X-RAY DIFFRACTION	99.5

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001890 (353 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA2G_03214 Search term: acetoin utilization protein

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000216271 histone deacetylase 10 [Source:HGNC Symbol;Acc:HGNC:18128] E-value: 1.7e-39 Percent Identity: 37.3

References