Pseudomonas aeruginosa 2192, PA2G_02991

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa 2192
GCF_000152545.1|latest
Locus Tag
PA2G_02991
Name
Replicon chromosome
Genomic location 3332340 - 3334328 (+ strand)

Cross-References

RefSeq ZP_04935578.1
GI 254242256
NCBI Locus Tag PA2G_02991
UniProtKB Acc A3LE16
UniProtKB ID A3LE16_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase
Synonyms
Evidence for Translation
Charge (pH 7) -3.52
Kyte-Doolittle Hydrophobicity Value -0.253
Molecular Weight (kDa) 74.4
Isoelectric Point (pI) 6.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
arnA arnA modifies lipid A with 4-amino-4-deoxy-L-arabinose (Ara4N) which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. arnA is found in E. coli and P. aeruginosa. [PMID:11021929, PMID:15939024] ARO:3002985 protein homolog model Perfect 1363.2 100.0 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002112 (427 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2G_02991

Human Homologs

Ensembl 110, assembly GRCh38.p14
UDP-glucuronate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:17729]
E-value: 1.5e-27
Percent Identity: 27.3
Ensembl 110, assembly GRCh38.p14
UDP-glucuronate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:17729]
E-value: 1.5e-27
Percent Identity: 27.3

References

No references are associated with this feature.